Telles-Correia, DBarbosa, AMega, IMateus, EMonteiro, E2015-03-102015-03-102009Transplant Proc. 2009 Apr;41(3):898-900http://hdl.handle.net/10400.17/2032OBJECTIVES: We sought to investigate the psychosocial determinants of quality of life at 6 months after transplantation. METHODS: A sample of liver transplant candidates (n = 60), composed of consecutive patients (25% with familial amyloid polyneuropathy [FAP]) attending outpatient clinics was assessed in the pretransplant period using the Neo Five Factor Inventory, Hospital Anxiety and depression Scale (HADS), Brief COPE, and SF-36, a quality-of-life, self-rating questionnaire. Six months after transplantation, these patients were assessed by means of the SF-36. RESULTS: Psychosocial predictors where found by means of multiple regression analysis. The physical component of quality of life at 6 months after transplantation was determined based upon coping strategies and physical quality of life in the pretransplant period (this model explained 32% of variance). The mental component at 6 months after transplantation was determined by depression in the pretransplant period and by clinical diagnoses of patients. Because FAP patients show a lower mental component of quality of life, this diagnosis explained 25% of the variance. CONCLUSIONS: Our findings suggested that coping strategies and depression measured in the pretransplant period are important determinants of quality of life at 6 months after liver transplantation.engHCC CHBPTAdaptation, PsychologicalAmyloid Neuropathies, Familial/surgeryAnxiety/epidemiologyDepression/epidemiologyHumansLiver Diseases/classificationLiver Diseases/surgeryLiver Transplantation/physiologyLiver Transplantation/psychologyLongitudinal StudiesPersonalityPsychologyQuality of LifeQuestionnairesRegression AnalysisRetrospective Studiesjournal article