Raimundo, PCoelho, SCabeleira, ADias, LGonçalves, M2015-06-302015-06-302010BMJ Case Rep. 2010 May 19;2010. pii: bcr0620091971http://hdl.handle.net/10400.17/2241The ovarian cystic teratoma is a rare cause of autoimmune haemolytic anaemia by warm antibodies, resistant to corticotherapy, with few case reports published in the medical literature. We present a case of a 45-year-old woman admitted to hospital due to general weakness. Laboratory studies revealed macrocytic anaemia, biochemical parameters of haemolysis and peripheral spherocytosis. The direct Coombs test was positive. Viral serologies, anti-nuclear antibodies, anti-double-stranded DNA antibodies and β2-microglobulin were negative. CT scan of the thorax, abdomen and pelvis showed a heterogeneous right anexial lesion. The patient was treated with corticotherapy without improvement of anaemia. Regression of extra-vascular haemolysis and normalisation of haemoglobin was obtained only after laparoscopic splenectomy and right ooforectomy, and the histopathology of the right anexial mass revealed a cystic teratoma. Previously published cases controlled the haemolysis by surgically removing the lesion associated with splenectomy.engHSJ MEDHSJ ANPATHSJ CIRAnemia, Hemolytic, Autoimmune/immunologyCoombs TestDiagnosis, DifferentialLaparoscopyOvarian Neoplasms/diagnosisOvarian Neoplasms/immunologyOvarian Neoplasms/surgeryOvariectomySplenectomyTeratoma/diagnosisTeratoma/immunologyTeratoma/surgeryTomography, X-Ray Computedjournal article