Gouveia, CBajanca-Lavado, MPMamede, RAraújo Carvalho, ARodrigues, FMelo-Cristino, JRamirez, MFriães, A2024-01-102024-01-102023Euro Surveill . 2023 Sep;28(36):2300427http://hdl.handle.net/10400.17/4780ince autumn 2022, observed numbers of paediatric invasive group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1UK sublineage (26/55) and more diverse emm12 isolates (12/55).engCOVID-19*ChildChromosome MappingPortugal / epidemiologyStreptococcal Infections* / diagnosisStreptococcal Infections* / epidemiologyStreptococcus pyogenes / geneticsUnited KingdomHDE INF PEDSustained Increase of Paediatric Invasive Streptococcus Pyogenes Infections Dominated by M1UK and Diverse Emm12 isolates, Portugal, September 2022 to May 2023journal article10.2807/1560-7917.ES.2023.28.36.2300427