Pereira, HCaldeira, DCampante Teles, RCosta, MCanas da Silva, Pda Gama Ribeiro, VBrandão, VMartins, DMatias, FPereira-Machado, FBaptista, JFarto e Abreu, PSantos, RDrummond, ACyrne de Carvalho, HCalisto, JSilva, JCPipa, JLMarques, JSousa, PFernandes, RCruz Ferreira, RRamos, SInfante Oliveira, Ede Sousa Almeida, M2018-08-072018-08-072018-04-24BMC Cardiovasc Disord. 2018 Apr 24;18(1):69.http://hdl.handle.net/10400.17/3019BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). RESULTS: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). CONCLUSIONS: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.engHSM CARCoronary Thrombosis/diagnosisCoronary Thrombosis/mortalityPortugalCoronary Thrombosis/surgeryHospital MortalityPercutaneous Coronary Intervention/adverse effectsPercutaneous Coronary Intervention/mortalityProtective FactorsRegistriesRetrospective StudiesRisk AssessmentRisk FactorsST Elevation Myocardial Infarction/diagnosisST Elevation Myocardial Infarction/mortalityST Elevation Myocardial Infarction/surgeryThrombectomy/adverse effectsThrombectomy/mortalityTime FactorsTreatment Outcomejournal article10.1186/s12872-018-0794-4