Trindade, FHaro, RRequena, L2016-03-312016-03-312009-04J Cutan Pathol. 2009 Apr;36(4):493-6http://hdl.handle.net/10400.17/2449Angiolymphoid hyperplasia with eosinophilia is a rare vascular proliferation characterized by single or multiple purplish, brownish papules and subcutaneous nodules, sometimes associated with pain or pruritus. This rare benign process occurs with a female predominance. Approximately 85% of the lesions occur in the skin of the head and neck; most of them are around the ear or on the forehead or scalp. Whether angiolymphoid hyperplasia with eosinophilia represents a benign neoplasm or an unusual reaction to varied stimuli, including trauma, the etiology remains unclear. Histopathologically, the lesions consist of a proliferation of blood vessels of variable size lined by large epithelioid endothelial cells and a variable inflammatory infiltrate of lymphocytes and eosinophils, sometimes with lymphoid follicle formation. The lesion is benign but may be persistent and is difficult to eradicate. We report on a case of a 58-year-old Caucasian man who presented a purplish pink dome-shaped tumor of size up to 8 cm in diameter located on the chest. We emphasize this case considering the unusual dimensions of the lesion (8 cm diameter) and the atypical location on the chest.engHSAC DERAngiolymphoid Hyperplasia with Eosinophilia/pathologyAngiolymphoid Hyperplasia with Eosinophilia/surgeryThorax/pathologyGiant Angiolymphoid Hyperplasia with Eosinophilia on the Chestjournal article10.1111/j.1600-0560.2008.01066.x