Boattini, MRodrigues, ANascimento, PLuz, KCCastelo Branco, SRodrigues, NCachado, PGarcia, T2015-10-222015-10-222015Acta Reumatol Port. 2015 Apr-Jun;40(2):190-2http://hdl.handle.net/10400.17/2315Propylthiouracil (PTU) is known to induce antineutrophil cytoplasmatic antibody (ANCA) seropositivity; however, small vessel vasculitis (SVV) with pulmonary and renal involvement is rare. We present the case of an 81-year-old woman on PTU treatment due to toxic nodular goitre who developed alveolar hemorrhage and rapidly progressive glomerulonephritis. The authors highlight the importance of early recognising drug-induced pulmonary-renal syndrome (PRS) in order to avoid unnecessary tests, a delay in the diagnosis and evolution to end-stage kidney disease or life-threatening conditions.engHSM MEDHCC NEFGlomerulonephritis/chemically inducedHemorrhage/chemically inducedLung Diseases/chemically inducedPropylthiouracil/adverse effectsAged, 80 and overjournal article