Coutinho Cruz, MSá Carvalho, RModas Daniel, PCruz Ferreira, R2018-03-092018-03-092017-10Rom J Anaesth Intensive Care. 2017 Oct;24(2):163-166.http://hdl.handle.net/10400.17/2939Anaphylaxis is life-threatening and should be addressed urgently. Its treatment is not without side effects and an accurate diagnosis must be made to prevent potential harm by the wrongful use of medication. A 46-year-old woman with hypertension treated with angiotensin converting enzyme inhibitor (ACEI) presented to the emergency department with non-pitting oedema of the face and limbs. A hasty diagnosis of anaphylaxis was made and intravenous adrenaline administered. The patient developed a myocardial infarction caused by coronary artery spasm that required invasive intervention. The initial clinical picture was resolved when the ACEI was discontinued unmasking a case of ACEI-induced angioedema. The correct differentiation of these two apparently similar clinical entities is of utmost importance in the management of emergency department patients.engHSM CARACEI-Induced AngioedemaAcute Myocardial InfarctionAdrenalineAnaphylaxisjournal article10.21454/rjaic.7518.242.crz