Machado Nogueira, JFreire, MJVila Nova, VJesus, G2021-11-242021-11-242021Case Rep Nephrol Dial. 2021 Aug 4;11(2):241-246.http://hdl.handle.net/10400.17/3924Tacrolimus is an immunosuppressive drug frequently used in solid organ transplant recipients. This drug has well-documented neuropsychiatric side effects in the literature, although emergence of psychotic symptoms is rare, being only described in a very few case reports. We present a case of a renal transplant recipient with no prior psychiatric history, who developed a severe psychosis secondary to supratherapeutic tacrolimus' blood concentrations. This case highlights the importance of clinical awareness to rare but severe neuropsychiatric effects due to tacrolimus use.engCHLC PSIQPsychosisTacrolimusNeurotoxicNeuropsychiatric Side Effectsjournal article10.1159/000515048.