Timóteo, ATAguiar Rosa, SGarcia Brás, PVidigal Ferreira, MJBettencourt, N2024-08-142024-08-142022J Clin Ultrasound . 2022 Oct;50(8):1084-1096.http://hdl.handle.net/10400.17/4992Amyloidosis is a systemic disease, characterized by deposition of amyloid fibrils in various organs, including the heart. For the diagnosis of cardiac amyloidosis (CA) it is required a high level of clinical suspicion and in the presence of clinical, laboratorial, and electrocardiographic red flags, a comprehensive multimodality imaging evaluation is warranted, including echocardiography, magnetic resonance, scintigraphy, and computed tomography, that will confirm diagnosis and define the CA subtype, which is of the utmost importance to plan a treatment strategy. We will review the use of multimodality imaging in the evaluation of CA, including the latest applications, and a practical flow-chart will sum-up this evidence.engHSM CARHumansAmyloid*EchocardiographyAmyloidosis* / diagnostic imagingAmyloidosis* / pathologyMultimodal Imaging / methodsRadionuclide Imagingjournal article10.1002/jcu.23271