Vieira, LCabugueira, ABorges, BCarvalho, VNoronha, MAbegão Pinto, LReina, MDutra Medeiros, M2021-08-132021-08-132016-06J Glaucoma. 2016 Jun;25(6):e576-80.http://hdl.handle.net/10400.17/3835Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy. Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded. Results: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P=0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P=0.09). Conclusion: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.engCHLC OFTAdultAgedFemaleMaleHumansMiddle AgedEpiretinal Membrane / diagnosisEpiretinal Membrane / epidemiologyEpiretinal Membrane / etiologyFollow-Up StudiesGlaucoma, Open-Angle / physiopathologyGlaucoma, Open-Angle / surgeryIncidenceIntraocular PressurePortugal / epidemiologyPostoperative Complications / epidemiologyTime FactorsRetrospective StudiesTomography, Optical CoherenceTrabeculectomy / adverse effectsVisual Acuityjournal article10.1097/IJG.0000000000000326.