Rego de Figueiredo, IVieira Alves, RDrummond Borges, DTorres, MLourenço, FAntunes, AMGruner, HPanarra, A2019-10-112019-10-112019Pulmonology. 2019 Sep - Oct;25(5):271-274.http://hdl.handle.net/10400.17/3317Pneumocystis pneumonia (PCP) is caused by the fungus Pneumocystis jirovecii, and its incidence has been on the rise in immunosuppressed patients without HIV. We performed a cross sectional study in patients with PCP and assessed demographic, clinical presentation and outcome measures such as mechanical ventilation and mortality differences between HIV and non-HIV patients. The two groups were statistically significantly different, with the HIV group being younger (45.5 years vs 55.9 years, p-value 0.001) and mostly composed of male patients (69% vs 31%, p-value <0.001). Also, the HIV patients had higher percentage of respiratory complaints (90% vs 68%, p-value 0.02) and lactate dehydrogenase elevation (73% vs 40%, p-value 0.001). In contrast, non-HIV patients had worse outcomes with higher incidence of invasive mechanical ventilation (23% vs 46%, p-value 0.005) and in-hospital mortality (13% vs 37%, p-value 0.002). These results reflect the literature and should raise awareness to a potentially fatal medical situation of increasing incidence.engHCC MEDHCC INFComorbidityCross-Sectional StudiesHIV Infections/epidemiologyHIV Infections/immunologyHospital MortalityImmunocompromised HostL-Lactate Dehydrogenase/bloodPneumonia, Pneumocystis/epidemiologyPneumonia, Pneumocystis/immunologyPneumonia, Pneumocystis/mortalityPortugal/epidemiologyRespiration, Artificial/statistics & numerical dataRetrospective Studiesjournal article10.1016/j.pulmoe.2019.04.003