Escoli, RSantos, PAndrade, SCarvalho, F2016-08-122016-08-122015Case Rep Nephrol. 2015;2015:298261http://hdl.handle.net/10400.17/2556Dabigatran is a direct thrombin inhibitor used as an alternative to warfarin for long term anticoagulation. Warfarin-related nephropathy is an increasingly recognized entity, but recent evidence suggests that dabigatran can cause a WRN-like syndrome. We describe a case of a biopsy-proven anticoagulant nephropathy related to dabigatran in a patient with IgA nephropathy and propose that, despite the base glomerular disease, acute kidney injury was due to tubular obstruction by red blood cells and heme-associated tubular injury, and through a mechanism involving inhibition of anticoagulation cascade and barrier abnormalities caused by molecular mechanisms.engHCC NEFDabigatranGlomerulonephritis, IGAjournal article10.1155/2015/298261