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Browsing by Author "Aguilar, S"

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  • HELLP Syndrome a Severe Form of Preeclampsia: a Comparative Study of Clinical and Laboratorial Parameters
    Publication . Campos, A; Gonçalves, A; Massa, AC; Amaral, P; Silva, P; Aguilar, S
    The objective of this study was to compare clinical, laboratorial, maternal and perinatal results between HELLP Syndrome and severe Preeclampsia. An observational study comparing women with HELLP Syndrome (n=71) to women with severe preeclampsia (n=253) was done. The authors analyzed the early course of the pathologies and the outcomes in both groups. HELLP syndrome occurred in 28% of all the cases and was more frequent at gestational age before 32 weeks (n=39 – 55%) than severe preeclampsia (n=108 - 42%), with more newborns weighting less than 1500g (27 – 38.6% vs 65 – 25.6%; p=0.036). Thrombocytopenia below 100 000/μL (aOR, 2.14; 95% CI, 1.49 – 3.06) and LDH>1 000 UI/L (aOR: 5.17; 95% CI 2.19 – 12.16) were risk factors for HELLP. Maternal morbidity (eclampsia, abruptio placentae, and acute renal failure) was similar in both cohorts; eight stillbirths (6 in severe preeclampsia and 2 in HELLP Syndrome) occurred. There were no maternal deaths. In conclusion, in this study the authors confirmed that HELLP Syndrome is a severe form of preeclampsia with an earlier presentation in pregnancy, worst laboratorial findings and more prematurity rates.
    2016Journal article Open access Show more
  • Parasitic Myoma: A Rare Presentation of a Common Disease
    Publication . Aguilar, S; Vasconcelos, C; Redondo, L; Fatela, A
    Parasitic myomas are a rare form of uterine leiomyomas. Distinction from other abdominal masses may be difficult, due to parasitic leiomyomas' variable anatomic locations and clinical manifestations. We describe the case of a 45 years-old woman, presenting with abdominal pain and a large pelvic mass that turned out to be a parasitic myoma at surgical assessment. Histological analysis confirmed the intraoperative suspicion. We intend to bring awareness to the inclusion of this condition in the differential diagnosis of pelvic masses, especially in women with risk factors for parasitic myomas, such as previous surgery for uterine fibromyomatosis or concomitant uterine myomas.
    2018Journal article Open access Show more
  • Pregnancy and Epilepsy
    Publication . Aguilar, S; Alves, MJ; Serrano, F
    Epilepsy is common among women of childbearing age. Maternal-fetal risk is slightly superior to general population, resulting from antiepileptic drugs' teratogenicity and seizures. Optimized disease control and screening for medication's adverse effects are crucial parts of prenatal care. Most pregnant women require chronic therapy to prevent seizures; definition of an effective and least teratogenic regime should be performed preconceptionally. Sodium valproate is the most teratogenic drug; teratogenicity also increases with polytherapy and medication dosage. Labour should take place in a qualified obstetrical and neonatal centre. Usually breastfeeding is safe. Regarding contraception, consider interactions between enzyme-inducing antiepileptics drugs and hormonal contraceptives
    2016Journal article Open access Show more