Repositório da Unidade Local de Saúde São José

Institution's Scientific Repository

The Repository of the Local Health Unit of São José is constituted by São José Hospital, Sto. António dos Capuchos Hospital, Sta. Marta Hospital, Dona Estefânia Hospital, Curry Cabral Hospital, Júlio de Matos Hospital, Dr. Alfredo da Costa Maternity, the Dr. Gama Pinto Ophthalmology Institute, the Health Centres of Central Lisbon and the Health Centre of Sacavém. It was created within the RCAAP (Portugal Open Access Science Repository) project framework and it aims to digitally divulge the scientific knowledge produced by its professionals as well as to allow open access to all of the knowledge gathered, centralised, preserved and released, so as to give greater visibility and impact to the investigation developed by the Local Health Unit of São José.

Useful Links

Find more about the Open Access Policy of Unidade Local de Saúde de São José!

Tel HSJ +351 218 841 2 80 / 40

Tel HDE +351 213 596 4 34 / 36

Email repositorio@ulssjose.min-saude.pt

Recent Submissions

Sex Dependence of Postoperative Pulmonary Complications - A Post Hoc Unmatched and Matched Analysis of LAS VEGAS.

Publication . Vermeulen, Tom D; Hol, Liselotte; Swart, Pien; Hiesmayr, Michael; Mills, Gary H; Putensen, Christian; Schmid, Werner; Serpa Neto, Ary; Severgnini, Paolo; Vidal Melo, Marcos F; Wrigge, Hermann; Hollmann, Markus W; Gama de Abreu, Marcelo; Schultz, Marcus J; Hemmes, Sabrine N; van Meenen, David M

Study objective: Male sex has inconsistently been associated with the development of postoperative pulmonary complications (PPCs). These studies were different in size, design, population and preoperative risk. We reanalysed the database of 'Local ASsessment of Ventilatory management during General Anaesthesia for Surgery study' (LAS VEGAS) to evaluate differences between females and males with respect to PPCs. Design, setting and patients: Post hoc unmatched and matched analysis of LAS VEGAS, an international observational study in patients undergoing intraoperative ventilation under general anaesthesia for surgery in 146 hospitals across 29 countries. The primary endpoint was a composite of PPCs in the first 5 postoperative days. Individual PPCs, hospital length of stay and mortality were secondary endpoints. Propensity score matching was used to create a similar cohort regarding type of surgery and epidemiological factors with a known association with development of PPCs. Main results: The unmatched cohort consisted of 9697 patients; 5342 (55.1%) females and 4355 (44.9%) males. The matched cohort consisted of 6154 patients; 3077 (50.0%) females and 3077 (50.0%) males. The incidence in PPCs was neither significant between females and males in the unmatched cohort (10.0 vs 10.7%; odds ratio (OR) 0.93 [0.81-1.06]; P = 0.255), nor in the matched cohort (10.5 vs 10.0%; OR 1.05 [0.89-1.25]; P = 0.556). New invasive ventilation occurred less often in females in the unmatched cohort. Hospital length of stay and mortality were similar between females and males in both cohorts. Conclusions: In this conveniently-sized worldwide cohort of patients receiving intraoperative ventilation under general anaesthesia for surgery, the PPC incidence was not significantly different between sexes. Registration: LAS VEGAS was registered at clinicaltrial.gov (study identifier NCT01601223).

2024-12Text

Open access

Bone Histomorphometry for the Diagnosis of Renal Osteodystrophy - a European Consensus Statement.

Publication . Lafage-Proust, Marie-Helene; Jørgensen, Hanne Skou; Bravenboer, Nathalie; Ferreira, Anibal; Bégin, Marie-Josée; Cannata-Andia, Jorge; Cejka, Daniel; Chavassieux, Pascale; Cohen-Solal, Martine; D'Haese, Patrick; Fahrleitner-Pammer, Astrid; Ferreira, Ana Carina; Fusaro, Maria; Gerbaix, Maude; Hamdy, Neveen; Hansen, Ditte; de Jongh, Renate; Kröger, Heikki; Lalayiannis, Alexander D; Salam, Syazrah; Spasovski, Goce; Shroff, Rukshana; Tong, XiaoYu; Trombetti, Andrea; Ureña, Pablo; Bacchetta, Justine; Mazzaferro, Sandro; Haarhaus, Mathias; Evenepoel, Pieter

Histomorphometric analysis of an iliac bone biopsy remains the gold standard for the diagnosis of renal osteodystrophy (ROD), which comprises various histological lesions induced by chronic kidney disease (CKD). ROD belongs to the framework of CKD-associated osteoporosis. The use of bone biopsy in the routine management of CKD-associated osteoporosis has decreased over the past decades for various reasons, including diminishing expertise in performing the procedure, and major variability in processing bone samples and reporting of results. In this context, the European Renal Osteodystrophy group, a part of the CKD-mineral and bone disorder working group of the European Renal Association launched an initiative to evaluate various issues related to bone histomorphometry in the context of ROD. To this effect, 28 experts from 14 European countries engaged in rounds of discussions to reach a consensus related to the bone biopsy procedure, sample handling, and reading and reporting findings. Key conclusions include a recommendation that all practitioners in this field move towards reporting diagnostic findings by the turnover, mineralization, and volume (TMV) classification and that external quality control is prioritized to ensure validity and reproducibility of results. The consensus group recognises that the lack of an accepted normative reference for bone histomorphometry is a barrier towards uniform diagnostic definitions and recommends further collaborative efforts in this area. Until these issues are solved, transparent reporting on the choice of reference and diagnostic definitions applied should be adhered to, both in clinical reports and research settings.

2025-10Review

Open access

Pulmonary Endarterectomy's Blind Spot: Is Echocardiography the Answer?

Publication . Timóteo, Ana Teresa; Galrinho, Ana

2025-08Text

Open access

Seizure Prediction in Cerebral Venous Thrombosis - a Retrospective Single-Centre Observational Study.

Publication . Faustino, Patrícia; Melancia, Diana

Cerebral venous thrombosis (CVT) accounts for 0.5-1% of all strokes and 24-50% of these patients develop acute symptomatic seizures (AS). Clinical and radiological characteristics have been associated with an increased risk of AS in CVT. We aimed to identify clinical and imaging predictors associated with a higher risk of AS in CVT patients.We conducted a single-centre, retrospective cohort study and included all patients with CVT admitted to our stroke unit between January/2011-December/2022. Our primary outcome was AS occurence. Clinical and radiological characteristics were compared through a logistic binary regression, followed by a multivariable analysis.We included 156 patients, 80.8% female and a mean age of 41.5 ± 15.2 years. Fifty-two patients (33.3%) had a seizure during follow-up, the majority as AS (30.1%). We found an increased risk of AS in patients with focal signs at presentation (OR 5.35), superior longitudinal sinus (SLS) or cortical vein involvement (OR 5.03; OR 3.94), hemorrhagic lesions or oedema (OR 3.88; OR 4.17) and lesions located in the frontal or the parietal lobe (OR 4.61; OR 4.61). A multivariable analysis was also conducted and only SLS involvement (OR 6.06), cortical vein involvement (OR 2.76) and hemorrhagic lesion (OR 3.47) remained statistically significant.Seizures occurred in about a third of our CVT patients, the majority as AS. Haemorrhagic lesions, SLS and cortical vein involvement had a stronger association with AS that may raise our awareness for the risk of seizures in this population during the acute phase.

2025-09Text

Open access

Dual Posteromedial Portal Technique: Arthroscopic Loop Suspensory Fixation-Posterior Cruciate Ligament Tibial Avulsion Fracture.

Publication . Ramos-Marques, Nuno; Campos, Vicente; Aguiar, Thiago; Torrinha Jorge, João

Posterior cruciate ligament avulsion fracture injuries have been associated with an increased risk of meniscal tears and premature patellofemoral/medial compartment osteoarthritis. Sports-related trauma is a common cause of posterior cruciate ligament avulsion fractures. Surgical management is recommended for displaced bony avulsion of the posterior cruciate ligament to stabilize the knee and prevent knee pain, nonunion, and osteoarthritis progression. This article discusses our preferred treatment using a loop suspensory fixation device through a dual posteromedial portal technique.

2025-02Text

Open access