Browsing by Author "Apers, J"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- Efficacy of Bariatric Surgery in Type 2 Diabetes Mellitus Remission: the Role of Mini Gastric Bypass/One Anastomosis Gastric Bypass and Sleeve Gastrectomy at 1 Year of Follow-up. A European surveyPublication . Musella, M; Apers, J; Rheinwalt, K; Ribeiro, R; Manno, E; Greco, F; Čierny, M; Milone, M; Di Stefano, C; Guler, S; Van Lessen, IM; Guerra, A; Maglio, MN; Bonfanti, R; Novotna, R; Coretti, G; Piazza, LBACKGROUND: A retrospective study was undertaken to define the efficacy of both mini gastric bypass or one anastomosis gastric bypass (MGB/OAGB) and sleeve gastrectomy (SG) in type 2 diabetes mellitus (T2DM) remission in morbidly obese patients (pts). METHODS: Eight European centers were involved in this survey. T2DM was preoperatively diagnosed in 313/3252 pts (9.62%). In 175/313 patients, 55.9% underwent MGB/OAGB, while in 138/313 patients, 44.1% received SG between January 2006 and December 2014. RESULTS: Two hundred six out of 313 (63.7 %) pts reached 1 year of follow-up. The mean body mass index (BMI) for MGB/OAGB pts was 33.1 ± 6.6, and the mean BMI for SG pts was 35.9 ± 5.9 (p < 0.001). Eighty-two out of 96 (85.4%) MGB/OAGB pts vs. 67/110 (60.9%) SG pts are in remission (p < 0.001). No correlation was found in the % change vs. baseline values for hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) in relation to BMI reduction, for both MGB/OAGB or SG (ΔFPG 0.7 and ΔHbA1c 0.4 for MGB/OAGB; ΔFPG 0.7 and ΔHbA1c 0.1 for SG). At multivariate analysis, high baseline HbA1c [odds ratio (OR) = 0.623, 95% confidence interval (CI) 0.419-0.925, p = 0.01], preoperative consumption of insulin or oral antidiabetic agents (OR = 0.256, 95% CI 0.137-0.478, p = <0.001), and T2DM duration >10 years (OR = 0.752, 95% CI 0.512-0.976, p = 0.01) were negative predictors whereas MGB/OAGB resulted as a positive predictor (OR = 3.888, 95% CI 1.654-9.143, p = 0.002) of diabetes remission. CONCLUSIONS: A significant BMI decrease and T2DM remission unrelated from weight loss were recorded for both procedures if compared to baseline values. At univariate and multivariate analyses, MGB/OAGB seems to outperform significantly SG. Four independent variables able to influence T2DM remission at 12 months have been identified.
- Esophageal and Gastric Malignancies After Bariatric Surgery: a Retrospective Global StudyPublication . Parmar, C; Zakeri, R; Abouelazayem, M; Shin, T; Aminian, A; Mahmoud, T; Abu Dayyeh, B; Wee, M; Fischer, L; Daams, F; Mahawar, K; Gallardo, C; Agustin, C; Wright, F; Fuente, I; Carbajo, M; Cal, P; Chisholm, J; Kow, L; Tan, M; Gan, P; Gananadha, S; Felsenreich, D; Prager, G; Matthys, C; Himpens, J; Focquet, M; Ramos, A; Nato, M; Vidal, T; Andalib, A; Siblini, A; Ferri, L; Abdarabo, L; Nevo, Y; Pescarus, R; Yang, W; Hamed, H; Liagre, A; Bergeat, D; Marie, De M; Martini, F; Regis, F; Genser, L; Skalli, M; Nedelcu, M; Smejkal, M; Kassir, R; Nicolas, R; Stier, C; Nedelcut, DS; Christodoulidis, G; Vennapusa, A; Kermansaravi, M; Raziel, A; Sakran, N; Oldani, A; Boru, C; Mécheri, F; Ciccarese, F; Cesana, G; Musella, M; Uccelli, M; Foletto, M; Auricchio, P; Olmi, S; Seki, Y; Kasteleijn, A; Van 'T Hof, G; Apers, J; Hart, J; Van De Sande, J; Takkenberg, M; Feskens, P; Snoekx, R; Plat, V; Sandvik, J; Kalinowski, P; Nabais, C; Al-Bahrani, A; Al Zoubi, M; Bettonica, C; Osorio, J; Tejedor-Tejada, J; Sanz, L; Cuadrado, M; Moorjani, R; Yannick, F; Suter, M; Borbély, Y; Joerg, Z; Barajas-Gamboa, J; Kroh, M; Kisiel, A; Kamocka, A; Immanuel, A; Sgromo, B; Gopinath, B; Khoo, D; Mukherjee, S; Pournaras, D; Underwood, T; Griffiths, E; Miller, G; Jaretzke, H; Dmitrewski, J; Wadley, M; Al-Housni, R; Gillies, R; Singhal, R; Preston, S; Robinson, S; Hawkins, W; Adamo, M; El Kalaawy, M; Gossage, J; Crawford, C; Jaruvongvanich, VBackground: Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized. Objective: To characterize EG malignancies after bariatric procedures. Setting: University Hospital, United Kingdom. Methods: We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition. Results: This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period. Conclusion: The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition.
- Petersen's Hernia after Mini (One Anastomosis) Gastric BypassPublication . Kular, KS; Prasad, A; Ramana, B; Baig, S; Mahir Ozmen, M; Valeti, M; Ribeiro, R; De Luca, M; Apers, J; Mahawar, KK