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Browsing by Author "Santos Coelho, J"

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  • Hepatectomia Esquerda Robótica. Abordagem Caudal
    Publication . Barros, I; Silva, S; Carrelha, S; Santos Coelho, J; Pinto Marques, H
    2021Journal article Open access Show more
  • Hepatic Abscess Due to Streptococcus Anginosus and Eikenella Corrodens, Secondary to Gastric Perforation by a Fish Bone
    Publication . Gonçalves, RJ; Murinello, A; Gomes da Silva, S; Santos Coelho, J; Lopes Santos, A; Sá Damásio, H
    Introduction: Foreign-body ingestion is a common event, but in only less than 1% of the cases complications occur. Hepatic abscesses induced by foreign-body penetration are rare. To date, there are only 62 reported cases of hepatic abscess secondary to fish bone perforation of the gastrointestinal tract. Case presentation: A 78-year-old male patient was admitted due to high fever and vomiting for 2 days, along with frequent eructations for the past 3 months. Abdominal ultrasound showed a liver abscess in the left lobe, and computed tomography revealed a hyperdense linear image that crossed the superior wall of the gastric antrum, contacting the liver lesion, suggestive of a foreign body, probably a fish bone. Blood cultures were positive with isolation of Streptococcus anginosus and Eikenella corrodens. Ultrasound-guided percutaneous drainage of the abscess was done, and S. anginosus was isolated in the pus. Surgical debridement and fish bone removal were performed; the patient completed 21 days of antibiotic therapy, with a favorable evolution. Conclusion: To the best of our knowledge, this is the first reported case of liver abscess caused by fish bone penetration with isolation of S. anginosus and E. corrodens. Bacterial coaggregation is one of the mechanisms that can explain their ability for causing invasive infections away from the oral cavity, by increasing their resistance to the innate immune system and survival of both species.
    2019-10Journal article Open access Show more
  • Predicting Function Delay with a Machine Learning Model: Improve the Long-term Survival of Pancreatic Grafts
    Publication . Vigia, E; Ramalhete, L; Barros, I; Chumbinho, B; Filipe, E; Pena, A; Bicho, L; Nobre, A; Carrelha, S; Corado, S; Sobral, M; Lamelas, J; Santos Coelho, J; Pinto Marques, H; Pico, P; Costa, S; Rodrigues, F; Bigotte Vieira, M; Magriço, R; Cotovio, P; Caeiro, F; Aires, I; Silva, C; Remédio, F; Martins, A; Ferreira, A; Paulino, J; Nolasco, F; Ribeiro, R
    The impact of delayed graft function on outcomes following various solid organ transplants is well documented and addressed in the literature. Delayed graft function following various solid organ transplants is associated with both short- and long-term graft survival issues. In a retrospective cohort study including 106 patients we evaluated whether pancreas graft survival differs according to moment of insulin therapy following simultaneous pancreaskidney transplant. As a result, we aimed to identify possible risk factors and build a machine-learning-based model that predicts the likelihood of dysfunction following SPK transplant patients based on day zero data after transplant, allowing to enhance pancreatic graft survival. Feature selection by Relief algorithm yielded donor features, age, cause of death, hemoglobin, gender, ventilation days, days in ICU, length of cardiac respiratory arrest and recipient features, gender, long-term insulin, dialysis type, time of diabetes mellitus, vPRA pre-Tx, number of HLA-A mismatches and PRDI, all contributed to the models' strength.
    2022Journal article Open access Show more