Publication
Epilepsy and Cerebral Palsy: Characteristics and Trends in Children Born in 1976 - 1998
| dc.contributor.author | Sellier, E | |
| dc.contributor.author | Uldall, P | |
| dc.contributor.author | Calado, E | |
| dc.contributor.author | Solveig, S | |
| dc.contributor.author | Torrioli, MG | |
| dc.contributor.author | Platt, MJ | |
| dc.contributor.author | Cans, C | |
| dc.date.accessioned | 2012-12-13T13:29:37Z | |
| dc.date.available | 2012-12-13T13:29:37Z | |
| dc.date.issued | 2012 | |
| dc.description.abstract | Background: Although epilepsy is common in children with cerebral palsy (CP), no data exists on prevalence rates of CP and epilepsy. Aims: To describe epilepsy in children with CP, and to examine the association between epilepsy and neonatal characteristics, associated impairments and CP subtypes. Methods: Data on 9654 children with CP born between 1976 and 1998 and registered in 17 European registers belonging to the SCPE network (Surveillance of Cerebral Palsy in Europe)were analyzed. Results: A total of 3424 (35%) children had a history of epilepsy. Among them, seventy-two percent were on medication at time of registration. Epilepsy was more frequent in children with a dyskinetic or bilateral spastic type and with other associated impairments. The prevalence of CP with epilepsy was 0.69 (99% CI, 0.66e0.72) per 1000 live births and followed a quadratic trend with an increase from 1976 to 1983 and a decrease afterwards. Neonatal characteristics independently associated with epilepsy were the presence of a brain malformation or a syndrome, a term or moderately preterm birth compared with a very premature birth, and signs of perinatal distress including neonatal seizures, neonatal ventilation and admission to a neonatal care unit. Conclusions: The prevalence of CP with epilepsy followed a quadratic trend in 1976e1998 and mirrored that of the prevalence of CP during this period. The observed relationship between epilepsy and associated impairments was expected; however it requires longitudinal studies to be better understood. | por |
| dc.identifier.citation | Eur J Paed Neurology. 2012; 16: 48-55 | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/876 | |
| dc.language.iso | eng | por |
| dc.publisher | Elsevier | por |
| dc.subject | Epilepsia | por |
| dc.subject | Paralisia Cerebral | por |
| dc.subject | Epidemiologia | por |
| dc.subject | Factores de Risco | por |
| dc.subject | HDE NEU PED | |
| dc.title | Epilepsy and Cerebral Palsy: Characteristics and Trends in Children Born in 1976 - 1998 | por |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 55 | por |
| oaire.citation.startPage | 48 | por |
| oaire.citation.volume | 16 | por |
| rcaap.rights | openAccess | por |
| rcaap.type | article | por |