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Adherence to the “Atrial Fibrillation Better Care” (ABC) Pathway in Patients with Atrial Fibrillation and Cancer: a Report From the ESC-EHRA EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registry

2022Journal article Open access
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dc.contributor.authorVitolo, M
dc.contributor.authorProietti, M
dc.contributor.authorMalavasi, V
dc.contributor.authorBonini, N
dc.contributor.authorRomiti, G
dc.contributor.authorImberti, J
dc.contributor.authorFauchier, L
dc.contributor.authorMarin, F
dc.contributor.authorNabauer, M
dc.contributor.authorPotpara, T
dc.contributor.authorDan, GA
dc.contributor.authorKalarus, Z
dc.contributor.authorMaggioni, A
dc.contributor.authorLane, D
dc.contributor.authorLip, G
dc.contributor.authorBoriani, G
dc.contributor.authorBoriani Chair, G
dc.contributor.authorLip, G
dc.contributor.authorTavazzi, L
dc.contributor.authorMaggioni, A
dc.contributor.authorDan, G
dc.contributor.authorPotpara, T
dc.contributor.authorNabauer, M
dc.contributor.authorMarin, F
dc.contributor.authorKalarus, Z
dc.contributor.authorFauchier, L
dc.contributor.authorGoda, A
dc.contributor.authorMairesse, G
dc.contributor.authorShalganov, T
dc.contributor.authorAntoniades, L
dc.contributor.authorTaborsky, M
dc.contributor.authorRiahi, S
dc.contributor.authorMuda, P
dc.contributor.authorBolao, I
dc.contributor.authorPiot, O
dc.contributor.authorNabauer, M
dc.contributor.authorEtsadashvili, K
dc.contributor.authorSimantirakis, E
dc.contributor.authorHaim, M
dc.contributor.authorAzhari, A
dc.contributor.authorNajafian, J
dc.contributor.authorSantini, M
dc.contributor.authorMirrakhimov, E
dc.contributor.authorKulzida, K
dc.contributor.authorErglis, A
dc.contributor.authorPoposka, L
dc.contributor.authorBurg, M
dc.contributor.authorCrijns, H
dc.contributor.authorErküner, Ö
dc.contributor.authorAtar, D
dc.contributor.authorLenarczyk, R
dc.contributor.authorOliveira, M
dc.contributor.authorShah, D
dc.contributor.authorSerdechnaya, E
dc.contributor.authorDan, G
dc.contributor.authorPotpara, T
dc.contributor.authorDiker, E
dc.contributor.authorLip, G
dc.contributor.authorLane, D
dc.date.accessioned2024-08-06T14:29:38Z
dc.date.available2024-08-06T14:29:38Z
dc.date.issued2022
dc.description.abstractBackground: Implementation of the Atrial fibrillation Better Care (ABC) pathway is recommended by guidelines on atrial fibrillation (AF), but the impact of adherence to ABC pathway in patients with cancer is unknown. Objectives: To investigate the adherence to ABC pathway and its impact on adverse outcomes in AF patients with cancer. Methods: Patients enrolled in the EORP-AF General Long-Term Registry were analyzed according to (i) No Cancer; and (ii) Prior or active cancer and stratified in relation to adherence to the ABC pathway. The composite Net Clinical Outcome (NCO) of all-cause death, major adverse cardiovascular events and major bleeding was the primary endpoint. Results: Among 6550 patients (median age 69 years, females 40.1%), 6005 (91.7%) had no cancer, while 545 (8.3%) had a diagnosis of active or prior cancer at baseline, with the proportions of full adherence to ABC pathway of 30.6% and 25.7%, respectively. Adherence to the ABC pathway was associated with a significantly lower occurrence of the primary outcome vs. non-adherence, both in 'no cancer' and 'cancer' patients [adjusted Hazard Ratio (aHR) 0.78, 95% confidence interval (CI): 0.66-0.92 and aHR 0.59, 95% CI 0.37-0.96, respectively]. Adherence to a higher number of ABC criteria was associated with a lower risk of the primary outcome, being lowest when 3 ABC criteria were fulfilled (no cancer: aHR 0.54, 95%CI: 0.36-0.81; with cancer: aHR 0.32, 95% CI 0.13-0.78). Conclusion: In AF patients with cancer enrolled in the EORP-AF General Long-Term Registry, adherence to ABC pathway was sub-optimal. Full adherence to ABC-pathway was associated with a lower risk of adverse events.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationEur J Intern Med . 2022 Nov:105:54-62.pt_PT
dc.identifier.doi10.1016/j.ejim.2022.08.004pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4968
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectHSM CARpt_PT
dc.subjectHumanspt_PT
dc.subjectAgedpt_PT
dc.subjectFemalept_PT
dc.subjectAnticoagulants / adverse effectspt_PT
dc.subjectAtrial Fibrillation* / epidemiologypt_PT
dc.subjectHemorrhage / chemically inducedpt_PT
dc.subjectNeoplasms* / complicationspt_PT
dc.subjectRegistriespt_PT
dc.subjectRisk Factorspt_PT
dc.subjectStroke* / epidemiologypt_PT
dc.titleAdherence to the “Atrial Fibrillation Better Care” (ABC) Pathway in Patients with Atrial Fibrillation and Cancer: a Report From the ESC-EHRA EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registrypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage62pt_PT
oaire.citation.startPage54pt_PT
oaire.citation.titleEuropean Journal of Internal Medicinept_PT
oaire.citation.volume105pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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