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RoPE Score As a Predictor of Recurrent Ischemic Events After Percutaneous Patent Foramen Ovale Closure

2018-11-28Journal article Open access
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dc.contributor.authorMorais, LA
dc.contributor.authorSousa, L
dc.contributor.authorFiarresga, A
dc.contributor.authorMartins, JD
dc.contributor.authorTimóteo, AT
dc.contributor.authorViveiros Monteiro, A
dc.contributor.authorSoares, C
dc.contributor.authorAgapito, A
dc.contributor.authorPinto, MF
dc.contributor.authorCruz Ferreira, R
dc.date.accessioned2020-02-05T16:05:46Z
dc.date.available2020-02-05T16:05:46Z
dc.date.issued2018-11-28
dc.description.abstractThe benefits of patent foramen ovale (PFO) closure for cryptogenic stroke secondary prevention are still debated. The Risk of Paradoxical Embolism (RoPE) study developed a score to improve patient selection for this procedure. We proposed to assess the validity of this score to assess the prognostic impact of PFO closure.From 2000 to 2014, all consecutive patients submitted to PFO closure were included in a prospective registry in a university center. The primary endpoint was recurrent ischemic cerebrovascular events and the secondary endpoints were all-cause, neurological, and cardiac mortality rates and new-onset atrial fibrillation (NOAF) rates. In total, 403 patients were included in the study (women: 52.1%; mean age: 44.7 ± 10.9 years). The mean follow-up period was 6.4 ± 3.7 years. Immediate success was achieved in 97% patients. There were 23 (5.8%) ischemic cerebrovascular events, 8 (2.0%) deaths, and 17 (4.3%) NOAFs. The mean RoPE score was 6.10 ± 1.79. Smoker status, coronary artery disease, lower RoPE score, and higher left atrial dimensions were predictors of the primary endpoint. However, a lower RoPE score and coronary artery disease remained independent predictors in multivariate analysis.RoPE score was shown to be an independent predictor of recurrent ischemic cerebrovascular events, and a score of ≤ 6 was shown to identify patients with significantly higher risk of mortality and recurrent ischemic events.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationInt Heart J. 2018 Nov 28;59(6):1327-1332.pt_PT
dc.identifier.doi10.1536/ihj.17-489pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3408
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherInternational Heart Journal Associationpt_PT
dc.subjectAdultpt_PT
dc.subjectBrain Ischemia/diagnosispt_PT
dc.subjectFemalept_PT
dc.subjectFollow-Up Studiespt_PT
dc.subjectForamen Ovale, Patent/complicationspt_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectPrognosispt_PT
dc.subjectProspective Studiespt_PT
dc.subjectRecurrencept_PT
dc.subjectStroke/etiologypt_PT
dc.subjectTreatment Outcomept_PT
dc.subjectDecision Support Techniquespt_PT
dc.subjectSecondary Preventionpt_PT
dc.subjectHSM CARpt_PT
dc.subjectHSM CAR PEDpt_PT
dc.subjectBrain Ischemia/etiology
dc.subjectBrain Ischemia/prevention & control
dc.subjectForamen Ovale, Patent/surgery
dc.subjectStroke/prevention & control
dc.titleRoPE Score As a Predictor of Recurrent Ischemic Events After Percutaneous Patent Foramen Ovale Closurept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1332pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage1327pt_PT
oaire.citation.titleInternational Heart Journalpt_PT
oaire.citation.volume59pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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