Repository logo
 
Publication

CODAP: a Multidisciplinary Consensus Among Portuguese Experts on the Definition, Detection and Management of Atherogenic Dyslipidemia

2019-08Journal article Open access
Simple item page
dc.contributor.authorMello e Silva, A
dc.contributor.authorAguiar, C
dc.contributor.authorSequeira Duarte, J
dc.contributor.authorCouto, L
dc.contributor.authorTeixeira Veríssimo, M
dc.contributor.authorMarques da Silva, P
dc.date.accessioned2021-06-23T15:01:04Z
dc.date.available2021-06-23T15:01:04Z
dc.date.issued2019-08
dc.description.abstractIntroduction and aims: Atherogenic dyslipidemia is an important contributor to residual cardiovascular (CV) risk, but it is underdiagnosed and undertreated. This study aimed to assess the opinion of Portuguese experts to generate a consensus concerning the diagnosis and treatment of atherogenic dyslipidemia, as well as to contribute toward standardization of clinical practice in this disorder. Methods: The study consisted in the application of a questionnaire to an expert panel, following a modified Delphi methodology. Results: The majority (88.4%) of the proposed items were found to be consensual. The expert panel recognized the importance of the atherogenic dyslipidemia phenotype, the role played by low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol as risk markers and therapeutic targets, the choice of statins as first-line lipid-lowering drugs, and the value of associating statins with fenofibrate as a means to reduce residual CV risk. However, the role played by triglycerides in CV risk and the therapeutic value of fibrates lacked consensus. Taking into consideration the state of the art and the opinions expressed in this study, the scientific committee developed a treatment algorithm aimed to improve the perception and treatment of atherogenic dyslipidemia. Conclusions: The experts involved in this study were shown to be familiar with the concept and the importance of atherogenic dyslipidemia. The few situations in which a consensus could not be found were mainly related to the interpretation and/or relevance of the available evidence.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRev Port Cardiol (Engl Ed). 2019 Aug;38(8):531-542.pt_PT
dc.identifier.doi10.1016/j.repc.2019.03.005pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3746
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectAtherosclerosispt_PT
dc.subjectBiomarkerspt_PT
dc.subjectCholesterol, LDLpt_PT
dc.subjectDyslipidemiaspt_PT
dc.subjectHumanspt_PT
dc.subjectHydroxymethylglutaryl-CoA Reductase Inhibitorspt_PT
dc.subjectHypolipidemic Agentspt_PT
dc.subjectPortugalpt_PT
dc.subjectRisk Factorspt_PT
dc.subjectConsensuspt_PT
dc.subjectDisease Managementpt_PT
dc.subjectHSM MEDpt_PT
dc.titleCODAP: a Multidisciplinary Consensus Among Portuguese Experts on the Definition, Detection and Management of Atherogenic Dyslipidemiapt_PT
dc.title.alternativeCODAP: um Consenso Multidisciplinar sobre a Definição, Diagnóstico e Tratamento da Dislipidemia Aterogénica em Portugalpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage542pt_PT
oaire.citation.issue8pt_PT
oaire.citation.startPage531pt_PT
oaire.citation.titleRevista Portuguesa de Cardiologiapt_PT
oaire.citation.volume38pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
RPC 2019 531.pdf
Size:
884.62 KB
Format:
Adobe Portable Document Format
Download

Collections

MED - Artigos