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Juvenile Dermatomyositis Forty Years On: Case Report

2018Journal article Open access
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dc.contributor.authorRego de Figueiredo, I
dc.contributor.authorGuerreiro Castro, S
dc.contributor.authorBernardino, V
dc.contributor.authorSilva Nunes, J
dc.contributor.authorAlves, P
dc.contributor.authorMoraes-Fontes, MF
dc.date.accessioned2018-10-22T12:16:08Z
dc.date.available2018-10-22T12:16:08Z
dc.date.issued2018
dc.description.abstractWe present a case report of a 42 year old female, diagnosed at the age of 3 with Juvenile Dermatomyositis. The clinical course was severe and refractory to immunosuppressive therapy. Currently, she is mostly affected by severe muscle atrophy, large joint contractures, calcinosis, and a lipodystrophy associated metabolic syndrome with hypertriglyceridemia, insulin resistance, high total testosterone and hepatic steatosis. She developed Hodgkin´s lymphoma in the course of her disease. Personalized therapeutic choices are discussed as regards juvenile dermatomyositis complications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationNeuromuscul Disord. 2018 Sep;28(9):791-797pt_PT
dc.identifier.doi10.1016/j.nmd.2018.06.011pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3086
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectCalcinosis/diagnosispt_PT
dc.subjectCalcinosis/pathologypt_PT
dc.subjectDermatomyositis/diagnosispt_PT
dc.subjectDermatomyositis/pathologypt_PT
dc.subjectHCC DAUTOIMpt_PT
dc.subjectHDE IMApt_PT
dc.subjectHCC ENDpt_PT
dc.subjectDisease Progression
dc.subjectInsulin Resistance
dc.subjectLipodystrophy/diagnosis
dc.subjectLipodystrophy/pathology
dc.subjectMetabolic Syndrome/diagnosis
dc.subjectMetabolic Syndrome/pathology
dc.subjectMuscular Atrophy/diagnosis
dc.subjectMuscular Atrophy/pathology
dc.subjectSeverity of Illness Index
dc.titleJuvenile Dermatomyositis Forty Years On: Case Reportpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage797pt_PT
oaire.citation.issue9pt_PT
oaire.citation.startPage791pt_PT
oaire.citation.volume28pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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