Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report

Santos, G; Sousa, L; João, A

http://hdl.handle.net/10400.17/1804

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Authors

Santos, G

Sousa, L

João, A

Abstract(s)

The paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab.

Keywords

HSAC DER Anti-Inflamatórios Efeitos Adversos Anticorpos Monoclonais Humanizados Biópsia Evolução da Doença Sarcoidose Doenças da Pele Resultado de Tratamento Factor de Necrose Tumoral Alfa