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Severe Megaloblastic Anaemia in an Infant

dc.contributor.authorRodrigues, V
dc.contributor.authorDias, A
dc.contributor.authorBrito, MJ
dc.contributor.authorGalvão, I
dc.contributor.authorCordeiro Ferreira, G
dc.date.accessioned2013-11-19T12:18:10Z
dc.date.available2013-11-19T12:18:10Z
dc.date.issued2011
dc.description.abstractVitamin B 12 or cobalamin deficiency, a rare clinical entity in pediatric age, is found most exclusively in breastfed infants, whose mothers are strictly vegetarian non-supplemented or with pernicious anaemia. In this article, the authors describe a 10-month-old infant admitted for vomiting, refusal to eat and prostration. The infant was exclusively breastfed and diffi culties in introduction of new foods were reported. Failure to thrive since 5 months of age was also noticed. Laboratory evaluation revealed severe normocytic normochromic anaemia and cobalamin defi cit. A diagnosis of α-thalassemia trait was also made. Maternal investigation showed autoimmune pernicious anaemia. This case shows the severity of vitamin B 12 deficiency and the importance of adopting adequate and precocious measures in order to prevent potentially irreversible neurologic damage.por
dc.identifier.citationBMJ Case Reports 2011 May 16 ; doi:10.1136/bcr.02.2011.3835por
dc.identifier.urihttp://hdl.handle.net/10400.17/1553
dc.language.isoengpor
dc.publisherBMJ Publishing Grouppor
dc.subjectVitamina B 12por
dc.subjectAnemia Megaloblásticapor
dc.subjectCriançapor
dc.subjectHDE PEDpor
dc.titleSevere Megaloblastic Anaemia in an Infantpor
dc.typejournal article
dspace.entity.typePublication
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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