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Anatomical Basis, Histological Findings and Hemodinamics in the Modern Perfusion Model for Human Corpses

dc.contributor.authorJúnior, E
dc.contributor.authorBettencourt-Pires, M
dc.contributor.authorAlves, S
dc.contributor.authorCasal, D
dc.contributor.authorPais, D
dc.contributor.authorGoyri O’neill, J
dc.contributor.authorVassilenko, V
dc.date.accessioned2023-07-12T14:43:59Z
dc.date.available2023-07-12T14:43:59Z
dc.date.issued2022
dc.description.abstractsSeveral modern human cadaveric fixation methods are subject to permanent evaluation. Formaldehyde is the oldest and still the most widely used method of embalming. However, the International Agency for Research on Cancer has proven its high carcinogenic potential and its use was banned, with the recommendation of research for better alternatives in the conservation of corpses. The embalming method of excellence, which preserves all features, while keeping the disinfectant properties against cadaveric decomposition was proposed by João Goyri O’Neill. Their method was considered “the most modern and efficient technique in cadaveric preservation”. The aim of this present study was to analyze the quality of this original perfusion technique, at the organic level, based on central and peripheral hemodynamics. The cadaveric material was embalmed through a pulsed arterial perfusion system, connected to an automatic intermittent pump, that permits stability of the microvascular network, as well as the computerized measurement of the main perfusion parameters, such as flow and pressure. This procedure ensures good preservation of color, elasticity, texture, flexibility and fresh appearance, for several years. The morphological characteristics of the organs exhibited astonishing similarity to the living organic tissues, even several years after embalming and high freezing. Microscopic analysis demonstrated preservation of the structure of vessels, such as the aorta. Further studies on the integrity of the endocardial layer of the heart will enable to adapt the intermittent perfusion pump system to best simulate cardiac rhythm and arterial pulse, during cadaveric surgical training.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Morphol Sci 2022;39:435-441pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4604
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBrazilian Society of Anatomy and the Panamerican Association of Anatomistspt_PT
dc.subjectEmbalmingpt_PT
dc.subjectGross anatomypt_PT
dc.subjectPerfusionpt_PT
dc.subjectHemodynamicspt_PT
dc.subjectBlood Vesselspt_PT
dc.subjectArteriespt_PT
dc.subjectHSJ ANPATpt_PT
dc.titleAnatomical Basis, Histological Findings and Hemodinamics in the Modern Perfusion Model for Human Corpsespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage441pt_PT
oaire.citation.startPage435pt_PT
oaire.citation.volume39pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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