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Warm Antibody Autoimmune Haemolytic Anaemia Associated with Ovarian Teratoma

2010Journal article Open access
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dc.contributor.authorRaimundo, P
dc.contributor.authorCoelho, S
dc.contributor.authorCabeleira, A
dc.contributor.authorDias, L
dc.contributor.authorGonçalves, M
dc.date.accessioned2015-06-30T15:21:26Z
dc.date.available2015-06-30T15:21:26Z
dc.date.issued2010
dc.description.abstractThe ovarian cystic teratoma is a rare cause of autoimmune haemolytic anaemia by warm antibodies, resistant to corticotherapy, with few case reports published in the medical literature. We present a case of a 45-year-old woman admitted to hospital due to general weakness. Laboratory studies revealed macrocytic anaemia, biochemical parameters of haemolysis and peripheral spherocytosis. The direct Coombs test was positive. Viral serologies, anti-nuclear antibodies, anti-double-stranded DNA antibodies and β2-microglobulin were negative. CT scan of the thorax, abdomen and pelvis showed a heterogeneous right anexial lesion. The patient was treated with corticotherapy without improvement of anaemia. Regression of extra-vascular haemolysis and normalisation of haemoglobin was obtained only after laparoscopic splenectomy and right ooforectomy, and the histopathology of the right anexial mass revealed a cystic teratoma. Previously published cases controlled the haemolysis by surgically removing the lesion associated with splenectomy.por
dc.identifier.citationBMJ Case Rep. 2010 May 19;2010. pii: bcr0620091971por
dc.identifier.urihttp://hdl.handle.net/10400.17/2241
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherBMJ Publishing Grouppor
dc.subjectHSJ MEDpor
dc.subjectHSJ ANPATpor
dc.subjectHSJ CIRpor
dc.subjectAnemia, Hemolytic, Autoimmune/immunologypor
dc.subjectCoombs Testpor
dc.subjectDiagnosis, Differentialpor
dc.subjectLaparoscopypor
dc.subjectOvarian Neoplasms/diagnosispor
dc.subjectOvarian Neoplasms/immunologypor
dc.subjectOvarian Neoplasms/surgerypor
dc.subjectOvariectomypor
dc.subjectSplenectomypor
dc.subjectTeratoma/diagnosispor
dc.subjectTeratoma/immunologypor
dc.subjectTeratoma/surgerypor
dc.subjectTomography, X-Ray Computedpor
dc.titleWarm Antibody Autoimmune Haemolytic Anaemia Associated with Ovarian Teratomapor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.titleBMJ Case Reportspor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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