Publication
Acute Upper Limb Ischemia, a Rare Presentation of Giant Cell Arteritis
| dc.contributor.author | Almeida-Morais, L | |
| dc.contributor.author | Galego, S | |
| dc.contributor.author | Marques, N | |
| dc.contributor.author | Pack, T | |
| dc.contributor.author | Rodrigues, H | |
| dc.contributor.author | Abreu, R | |
| dc.contributor.author | Vasconcelos, L | |
| dc.contributor.author | Marques, H | |
| dc.contributor.author | Sousa Guerreiro, A | |
| dc.date.accessioned | 2016-05-03T15:45:21Z | |
| dc.date.available | 2016-05-03T15:45:21Z | |
| dc.date.issued | 2016-03-19 | |
| dc.description.abstract | Giant cell arteritis (GCA) is a systemic large vessel vasculitis, with extracranial arterial involvement described in 10-15% of cases, usually affecting the aorta and its branches. Patients with GCA are more likely to develop aortic aneurysms, but these are rarely present at the time of the diagnosis. We report the case of an 80-year-old Caucasian woman, who reported proximal muscle pain in the arms with morning stiffness of the shoulders for eight months. In the previous two months, she had developed worsening bilateral arm claudication, severe pain, cold extremities and digital necrosis. She had no palpable radial pulses and no measurable blood pressure. The patient had normochromic anemia, erythrocyte sedimentation rate of 120 mm/h, and a negative infectious and autoimmune workup. Computed tomography angiography revealed concentric wall thickening of the aorta extending to the aortic arch branches, particularly the subclavian and axillary arteries, which were severely stenotic, with areas of bilateral occlusion and an aneurysm of the ascending aorta (47 mm). Despite corticosteroid therapy there was progression to acute critical ischemia. She accordingly underwent surgical revascularization using a bilateral carotid-humeral bypass. After surgery, corticosteroid therapy was maintained and at six-month follow-up she was clinically stable with reduced inflammatory markers. GCA, usually a chronic benign vasculitis, presented exceptionally in this case as acute critical upper limb ischemia, resulting from a massive inflammatory process of the subclavian and axillary arteries, treated with salvage surgical revascularization. | pt_PT |
| dc.identifier.citation | Rev Port Cardiol. 2016 Apr;35(4):237.e1-4 | pt_PT |
| dc.identifier.doi | 10.1016/j.repc.2015.09.028 | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/2461 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Sociedade Portuguesa de Cardiologia | pt_PT |
| dc.subject | HSM CAR | pt_PT |
| dc.subject | HSM MED | pt_PT |
| dc.subject | HSM CIR VASC | pt_PT |
| dc.subject | HSM IMA | pt_PT |
| dc.subject | Aorta | pt_PT |
| dc.subject | Arm/blood supply | pt_PT |
| dc.subject | Giant Cell Arteritis/diagnosis | pt_PT |
| dc.subject | Ischemia/etiology | |
| dc.title | Acute Upper Limb Ischemia, a Rare Presentation of Giant Cell Arteritis | pt_PT |
| dc.title.alternative | Isquemia Crítica dos Membros Superiores, uma Apresentação Rara de Arterite de Células Gigantes | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | e4 | pt_PT |
| oaire.citation.startPage | e1 | pt_PT |
| oaire.citation.title | Revista Portuguesa de Cardiologia | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |