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Multidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory Status Epilepticus and Nontuberculous Mycobacterial CNS Infections in the ICU: A Case Report.

dc.contributor.authorBatarda Sena, Pedro Manuel
dc.contributor.authorFerro, Margarida
dc.contributor.authorAlves Cabrita, Joana
dc.contributor.authorPontinha, Carlos
dc.contributor.authorMestre, Ana
dc.contributor.authorOliveira, Mário
dc.contributor.authorBento, Luis
dc.date.accessioned2025-06-11T11:14:25Z
dc.date.available2025-06-11T11:14:25Z
dc.date.issued2024-12
dc.description.abstractThe diagnosis and management of complex neurological conditions such as New-Onset Refractory Status Epilepticus (NORSE) and central nervous system (CNS) infections caused by non-tuberculous mycobacteria (NTM) pose substantial difficulties in intensive care units (ICUs). This article combines a case report and a literature review that explores the diagnostic dilemmas and therapeutic strategies for these critical conditions. We report the case of an 83-year-old female with chronic granulomatous meningitis secondary to NTM, presenting a challenging diagnostic and complex management complexity typical of such a rare disease through a period time of five years. Her case emphasized the importance of a multidisciplinary approach in such cases, as the interplay between neurology and intensive care was vital. The need for new molecular diagnostic technologies is shown to be of high significance in identifying the causative pathogens and improving patient outcomes in these rare but critical conditions.eng
dc.identifier.citationCureus . 2024 Dec 26;16(12):e76449.
dc.identifier.doi10.7759/cureus.76449
dc.identifier.pmid39867002
dc.identifier.urihttp://hdl.handle.net/10400.17/5095
dc.language.isoeng
dc.peerreviewedyes
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCentral Nervous System
dc.subjectCentral Nervous System Infections
dc.subjectDiagnostic Tools
dc.subjectGranulomatous Meningitis
dc.subjectIntensive Care
dc.subjectIntensive Care Unit
dc.subjectMolecular Diagnostics
dc.subjectNew-Onset Refractory Status Epilepticus
dc.subjectNontuberculous Mycobacterial Infections
dc.titleMultidisciplinary Approaches and Molecular Diagnostics in New-Onset Refractory Status Epilepticus and Nontuberculous Mycobacterial CNS Infections in the ICU: A Case Report.eng
dc.typetext
dspace.entity.typePublication
oaire.citation.issue12
oaire.citation.startPagee76449
oaire.citation.titleCureus
oaire.citation.volume16
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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