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Initial Experience of Superb Microvascular Imaging for Key Cardiac Views in Foetal Assessment before 15 Weeks Gestation

dc.contributor.authorJabak, S
dc.contributor.authorVigneswaran, T
dc.contributor.authorCharakida, M
dc.contributor.authorKasapoglu, T
dc.contributor.authorCruz, J
dc.contributor.authorSimpson, J
dc.contributor.authorZidere, V
dc.date.accessioned2022-03-03T15:37:59Z
dc.date.available2022-03-03T15:37:59Z
dc.date.issued2020
dc.description.abstractBackground: In the first trimester, ultrasound confirmation of normal or abnormal cardiac anatomy is difficult. B-mode and colour flow Doppler (CFD) are used to assess the foetal heart. Superb microvascular imaging (SMI) can visualise blood flow within the heart and vessels in early gestation. Objective: We report an initial experience of SMI for visualisation of normal and abnormal cardiac anatomy in the first trimester. Methods: Transabdominal foetal echocardiography was performed between 11 + 6 and 14 + 3 weeks (Aplio 500 US system, Toshiba Medical Systems, Tokyo, Japan) from January 2017 to December 2017. All scans were performed at a tertiary foetal cardiology unit. To assess the potential utility of the technique for early gestation screening, normal scans were reviewed by foetal medicine trainees with respect to the B-mode, CFD and SMI. Three key views were selected to compare modalities: the 4-chamber view, outflow tracts and the 3-vessel and trachea view (VTV). Visualisation rates of key echocardiographic features of significant cardiac abnormalities by SMI were reviewed. Results: Fifty-five normal echocardiograms and 34 cardiac abnormalities were included. In the normal heart, when B-mode, CFD and SMI were assessed separately, SMI had the highest rate of visualisation of 4-chamber, outflow tracts and 3-VTV (93, 85 and 83%, respectively). Intra-observer reliability was moderate for SMI of the 3 standard views (kappa 1, 0.64 and 0.64); inter-observer for 4-chamber and outflow tract views was moderate (kappa 0.64 and 0.77). In 29/34 abnormal cases, SMI showed key features, enhancing greyscale visualisation. Conclusion: SMI has potential to become a useful, complementary modality for early foetal echocardiography. Further prospective studies are warranted to establish the place of the technique in assessment of the first trimester foetal heart.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationFetal Diagn Ther. 2020;47(4):268-276.pt_PT
dc.identifier.doi10.1159/000502839.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3982
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherKargerpt_PT
dc.subjectMAC MED MAFpt_PT
dc.subjectFemalept_PT
dc.subjectHumanspt_PT
dc.subjectEchocardiography, Doppler, Color / methods*pt_PT
dc.subjectFetal Heart / diagnostic imaging*pt_PT
dc.subjectPregnancypt_PT
dc.subjectHeart Defects, Congenital / diagnostic imaging*pt_PT
dc.subjectPregnancy Trimester, Firstpt_PT
dc.subjectProspective Studiespt_PT
dc.subjectUltrasonography, Prenatal / methods*pt_PT
dc.titleInitial Experience of Superb Microvascular Imaging for Key Cardiac Views in Foetal Assessment before 15 Weeks Gestationpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage276pt_PT
oaire.citation.startPage268pt_PT
oaire.citation.titleFetal Diagnosis and Therapypt_PT
oaire.citation.volume47pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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