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Self-Reported Low-Energy Fractures and Associated Risk Factors in People with Diabetes: a National Population-Based Study

2019Journal article Open access
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dc.contributor.authorFurtado, S
dc.contributor.authorRodrigues, A
dc.contributor.authorDias, S
dc.contributor.authorBranco, J
dc.contributor.authorCanhão, H
dc.date.accessioned2021-08-05T13:27:47Z
dc.date.available2021-08-05T13:27:47Z
dc.date.issued2019
dc.description.abstractAims: Clinical risk factors and bone mineral densitometry underestimate low-energy fracture (LEF) risk in people with diabetes. We aim to estimate the prevalence of LEF in diabetics, compare with nondiabetics; and evaluate possible predictors of LEF in people with diabetes. Methods: Cross-sectional, population-based study in Portuguese subjects over 40 years-old. Estimates computed as weighted proportions/means, considering sample design. Multivariate logistic regression models to evaluate the association of diabetes and LEF; and predictors of LEF in diabetics. Results: 7675 subjects were analysed, of which 1173 reported diabetes. Diabetics were older (mean age 66.0 ± 11.49y), more frequently reported osteoporosis and falls in the previous 12 months (32.4% vs. 22.9%). Prevalence of self-reported LEF was 16.2% (95% CI:13.68-19.13) among diabetics (vs. 13.3%, 95% CI:12.14-14.57, in nondiabetics); OR for the association diabetes and LEF:1.26, 95% CI:1.01-1.58, p = 0.045 (in women, adjusted OR:1.41, 95% CI:1.05-1.89, p = 0.02). Thirty percent of diabetics reported at least one major LEF and 70% in other sites. In diabetics, LEF was independently associated with self-reported osteoporosis and falls in the previous 12 months. Conclusion: People with diabetes reported more falls and had higher prevalence of self-reported LEF. Self-reported osteoporosis and falls were associated with LEF in diabetics. Our findings emphasize the need for fracture and falls preventive measures in diabetics.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationDiabetes Res Clin Pract. 2019 Jan;147:93-101.pt_PT
dc.identifier.doi10.1016/j.diabres.2018.11.015.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3787
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectHSJ MEDpt_PT
dc.subjectCross-Sectional Studiespt_PT
dc.subjectDiabetes Complications/complicationspt_PT
dc.subjectAdultpt_PT
dc.subjectAgedpt_PT
dc.subjectFemalept_PT
dc.subjectFractures, Bone/etiologypt_PT
dc.subjectFractures, Bone/pathologypt_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectResearch Designpt_PT
dc.subjectRisk Factorspt_PT
dc.subjectSelf Reportpt_PT
dc.titleSelf-Reported Low-Energy Fractures and Associated Risk Factors in People with Diabetes: a National Population-Based Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage101pt_PT
oaire.citation.startPage93pt_PT
oaire.citation.titleDiabetes Research and Clinical Practicept_PT
oaire.citation.volume147pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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