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A Rare Malignancy in the Post -Transplant Period: Myeloma Cast Nephropathy

dc.contributor.authorMesquita, I
dc.contributor.authorViana, H
dc.contributor.authorPossante, M
dc.contributor.authorJoão, C
dc.contributor.authorCarvalho, S
dc.contributor.authorSilva, C
dc.contributor.authorAires, I
dc.contributor.authorFerreira, A
dc.contributor.authorRemédio, F
dc.contributor.authorCarvalho, F
dc.contributor.authorNolasco, F
dc.date.accessioned2018-12-04T12:46:55Z
dc.date.available2018-12-04T12:46:55Z
dc.date.issued2016
dc.description.abstractMyeloma-associated renal disorders are rare events among renal transplants and can occur as recurrent or de novo disease. We describe an unusual case of renal allograft dysfunction due to myeloma cast nephropathy occurring 19 years after having received a renal transplant in a patient with no prior history of multiple myeloma or monoclonal gammopathy preceding transplantation. Our patient was treated with five cycles of chemotheraphy(bortezomib, melphalan and steroids), which resulted in short-term improvement in allograft dysfunction and complete haematological remission. The longer patient and graft survival after renal transplantation make post-transplant lymphoproliferative disease more frequent. Multiple myeloma after kidney transplant is rare and an elevated index of suspicion is necessary to make a timely diagnosis of this serious disease. Further work is needed to identify the best treatment options for these patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPort J Nephrol Hypert 2016; 30(4): 298-302pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3128
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedade Portuguesa de Nefrologiapt_PT
dc.subjectKidney Transplantationpt_PT
dc.subjectMyelomapt_PT
dc.subjectPost-Transplantpt_PT
dc.subjectNephropathypt_PT
dc.subjectHCC NEFpt_PT
dc.titleA Rare Malignancy in the Post -Transplant Period: Myeloma Cast Nephropathypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage302pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage298pt_PT
oaire.citation.volume30pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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