Repository logo
 
Publication

Serum Trace Elements in Dysphagic Gastrostomy Candidates Before Endoscopic Gastrostomy for Long Term Enteral Feeding

2016-06Journal article Open access
Simple item page
dc.contributor.authorSantos, CA
dc.contributor.authorFonseca, J
dc.contributor.authorCarolino, E
dc.contributor.authorSousa Guerreiro, A
dc.date.accessioned2016-05-03T15:56:09Z
dc.date.available2016-05-03T15:56:09Z
dc.date.issued2016-06
dc.description.abstractBACKGROUND & AIMS: Patients who underwent endoscopic gastrostomy (PEG) present protein-energy malnutrition, but little is known about Trace Elements (TE), Zinc (Zn), Copper (Cu), Selenium (Se), Iron (Fe), Chromium (Cr). Our aim was the evaluation of serum TE in patients who underwent PEG and its relationship with serum proteins, BMI and nature of underlying disorder. METHODS: A prospective observational study was performed collecting: patient's age, gender, underlying disorder, NRS-2002, BMI, serum albumin, transferrin and TE concentration. We used ferrozine colorimetric method for Fe; Inductively Coupled Plasma-Atomic Emission Spectroscopy for Zn/Cu; Furnace Atomic Absorption Spectroscopy for Se/Cr. The patients were divided into head and neck cancer (HNC) and neurological dysphagia (ND). RESULTS: 146 patients (89 males), 21-95 years: HNC-56; ND-90. Low BMI in 78. Low values mostly for Zn (n = 122) and Fe (n = 69), but less for Se (n = 31), Cu (n = 16), Cr (n = 7); low albumin in 77, low transferrin in 94 and 66 with both proteins low. Significant differences between the groups of underlying disease only for Zn (t140.326 = -2,642, p < 0.01) and a correlation between proteins and TE respectively albumin and Zn (r = 0.197, p = 0.025), and albumin and Fe (r = 0.415, p = 0.000). CONCLUSIONS: When gastrostomy was performed, patients display low serum TE namely Zn, but also Fe, less striking regarding others TE. It was related with prolonged fasting, whatever the underlying disease. Low proteins were associated with low TE. Teams taking care of PEG-patients should use Zn supplementation and include other TE evaluation as part of the nutritional assessment of PEG candidates.pt_PT
dc.identifier.citationClin Nutr. 2016 Jun;35(3):718-23pt_PT
dc.identifier.doi10.1016/j.clnu.2015.05.006pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2462
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectHSM MEDpt_PT
dc.subjectBiomarkers/bloodpt_PT
dc.subjectCombined Modality Therapypt_PT
dc.subjectDeficiency Diseases/diagnosispt_PT
dc.subjectDeficiency Diseases/epidemiologypt_PT
dc.subjectDeficiency Diseases/etiologypt_PT
dc.subjectDeficiency Diseases/prevention & control
dc.subjectDeglutition Disorders/blood
dc.subjectDeglutition Disorders/physiopathology
dc.subjectDeglutition Disorders/surgery
dc.subjectDeglutition Disorders/therapy
dc.subjectEnteral Nutrition
dc.subjectGastrostomy
dc.subjectNutrition Assessment
dc.subjectNutritional Status
dc.subjectPortugal/epidemiology
dc.subjectProspective Studies
dc.subjectProtein-Energy Malnutrition/diagnosis
dc.subjectProtein-Energy Malnutrition/epidemiology
dc.subjectProtein-Energy Malnutrition/etiology
dc.subjectProtein-Energy Malnutrition/prevention & control
dc.subjectRisk
dc.subjectSpectrophotometry, Atomic
dc.subjectTrace Elements/blood
dc.subjectTrace Elements/deficiency
dc.titleSerum Trace Elements in Dysphagic Gastrostomy Candidates Before Endoscopic Gastrostomy for Long Term Enteral Feedingpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage723pt_PT
oaire.citation.startPage718pt_PT
oaire.citation.titleClinical Nutritionpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Clin Nutr 2016.pdf
Size:
243.79 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

MED - Artigos