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Boundaries of a Systemic Disease: a Protean Presentation of Giant Cell Arteritis

2020Journal article Open access
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dc.contributor.authorMesquita, A
dc.contributor.authorCamara, L
dc.contributor.authorPatrício, C
dc.contributor.authorBrotas, V
dc.date.accessioned2021-11-24T16:23:34Z
dc.date.available2021-11-24T16:23:34Z
dc.date.issued2020
dc.description.abstractA 60-year-old man was hospitalised with persistent fever, arm pain, dry cough and cholestasis. Diagnostic workup was remarkable for elevated inflammatory markers. Infectious diseases and autoimmune screening were negative. Imaging modalities excluded a neoplastic aetiology. Liver biopsy was negative for granulomatous or lymphomatous infiltrations. Giant cell arteritis (GCA) was suspected, but temporal artery Doppler ultrasound and biopsy were non-diagnostic. A positron emission tomography scan showed intense metabolic uptake in large vessels suggesting the diagnosis of GCA. Prednisolone was initiated with clinical and analytical improvement. At 1-year follow-up, there were no relapses and the patient remains symptom free.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationBMJ Case Rep. 2020 Mar 25;13(3):e232234.pt_PT
dc.identifier.doi10.1136/bcr-2019-232234.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3926
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJpt_PT
dc.subjectHSAC MEDpt_PT
dc.subjectMalept_PT
dc.subjectHumanspt_PT
dc.subjectMiddle Aged
dc.subjectAnti-Inflammatory Agents, Non-Steroidal
dc.subjectAspirin / therapeutic use*
dc.subjectCholestasis
dc.subjectCough
dc.subjectDiagnosis, Differential
dc.subjectDrug Therapy, Combination
dc.subjectFever of Unknown Origin
dc.subjectGiant Cell Arteritis / diagnostic imaging*
dc.subjectGiant Cell Arteritis / drug therapy*
dc.subjectGlucocorticoids / therapeutic use
dc.subjectPositron-Emission Tomography
dc.subjectPrednisolone / therapeutic use*
dc.titleBoundaries of a Systemic Disease: a Protean Presentation of Giant Cell Arteritispt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.startPagee232234pt_PT
oaire.citation.titleBMJ Case Reportspt_PT
oaire.citation.volume13pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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