Hodgkin's Lymphoma in Crohn's Disease Treated with Infliximab

Carvalho, D; Russo, P; Bernardes, C; Saiote, J; Ramos, G; Mascarenhas, L; Borges, N; Ramos, J

http://hdl.handle.net/10400.17/2930

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
GE Port J Gastro 2017 279.pdf		568.57 KB	Adobe PDF	Download

Send Feedback

Authors

Abstract(s)

INTRODUCTION: Lymphoproliferative disorders, particularly non-Hodgkin's and Hodgkin's lymphomas, are rare in patients with inflammatory bowel diseases. The use of thiopurines and infection by Epstein-Barr virus are well-known cofactors that can raise its prevalence. Other risk factors such as disease activity and biological treatment are the subject of discussion, without enough data in the literature to confirm a potential association. METHODS: We report a case of Hodgkin's lymphoma in a patient who had been treated with azathioprine and was on long-term monotherapy with infliximab. CONCLUSIONS: We stress the importance of recognizing the possible occurrence of a lymphoproliferative disorder in association with anti-tumor necrosis factor-α therapy.