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Blastic Plasmacytoid Dendritic Cell Neoplasm

dc.contributor.authorLencastre, A
dc.contributor.authorFarinha, P
dc.contributor.authorCabete, J
dc.contributor.authorFerreira, G
dc.contributor.authorJoão, A
dc.contributor.authorLestre, S
dc.date.accessioned2013-12-20T17:46:51Z
dc.date.available2013-12-20T17:46:51Z
dc.date.issued2013
dc.description.abstractBlastic plasmacytoid dendritic cell neoplasm is a rare and aggressive hematodermic neoplasia with frequent cutaneous involvement and leukemic dissemination. We report the case of a 76-year-old man with a 2 month history of violaceous nodules and a tumor with stony consistency, located on the head, and mandibular, cervical and supraclavicular lymphadenopathies. Multiple thoracic and abdominal adenopathies were identified on computerized tomography. Flow cytometry analysis of the skin, lymph node and bone marrow biopsies demonstrated the presence of plasmocytoid dendritic cell neoplastic precursor cells (CD4+, CD45+, CD56+ and CD123+ phenotype). After initial clinical and laboratorial complete remission with chemotherapy, the patient died due to relapse of the disease associated with the appearance of a cervical mass with medullary compromise.por
dc.identifier.citationAn Bras Dermatol. 2013 Nov-Dec;88(6 Suppl 1):158-61por
dc.identifier.urihttp://hdl.handle.net/10400.17/1607
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherScielopor
dc.subjectBiópsiapor
dc.subjectCélulas Dendríticaspor
dc.subjectMedula Ósseapor
dc.subjectLeucemia/Patologiapor
dc.subjectHSAC DERpor
dc.subjectResultado Fatal
dc.subjectCitometria de Fluxo
dc.subjectInvasão Neoplásica
dc.subjectPele
dc.subjectNeoplasias da Pele
dc.titleBlastic Plasmacytoid Dendritic Cell Neoplasmpor
dc.title.alternativeNeoplasia Blástica de Células Dendríticas Plasmocitóidespor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage161por
oaire.citation.startPage158por
oaire.citation.titleAnais Brasileiros de Dermatologiapor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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