Publication
Primary Biliary Cholangitis: a Rare Diagnosis During Pregnancy
| dc.contributor.author | Inês Felizardo Lopes, I | |
| dc.contributor.author | Dos Reis, CP | |
| dc.contributor.author | Alves, MJ | |
| dc.contributor.author | Calinas, F | |
| dc.contributor.author | Borges, MA | |
| dc.date.accessioned | 2023-04-12T15:04:31Z | |
| dc.date.available | 2023-04-12T15:04:31Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Primary biliary cholangitis is an autoimmune disease that mostly affects women. It is uncommon in women of childbearing age and the diagnosis during pregnancy is rare and can be challenging. Described here is a case of primary biliary cholangitis first manifesting during pregnancy, with the onset of pruritus, jaundice, biochemical liver abnormalities and positive antimitochondrial antibodies. Although treatment with ursodeoxycholic acid was started at the time of diagnosis, there was a progressive worsening of cholestatic biochemical markers throughout pregnancy. In addition, fasting hyperglycemia with polyhydramnios was diagnosed, consistent with gestational diabetes. She had a spontaneous preterm delivery at 31 weeks of gestation, of a newborn who was admitted to the neonatal intensive care unit but who subsequently had no long-term sequelae of preterm delivery. A maternal postpartum flare occurred. Treatment with ursodeoxycholic acid was well tolerated during pregnancy and lactation. | pt_PT |
| dc.description.version | info:eu-repo/semantics/publishedVersion | pt_PT |
| dc.identifier.citation | Obstet Med . 2022 Dec;15(4):273-275. | pt_PT |
| dc.identifier.uri | http://hdl.handle.net/10400.17/4483 | |
| dc.language.iso | eng | pt_PT |
| dc.peerreviewed | yes | pt_PT |
| dc.publisher | Sage | pt_PT |
| dc.subject | Cholestasis | pt_PT |
| dc.subject | Liver disease | pt_PT |
| dc.subject | Pregnancy | pt_PT |
| dc.subject | Primary biliary cholangitis | pt_PT |
| dc.subject | MAC OBS | pt_PT |
| dc.subject | HSJ MED | pt_PT |
| dc.subject | MAC MED | pt_PT |
| dc.subject | HSAC GAS | pt_PT |
| dc.title | Primary Biliary Cholangitis: a Rare Diagnosis During Pregnancy | pt_PT |
| dc.type | journal article | |
| dspace.entity.type | Publication | |
| oaire.citation.endPage | 275 | pt_PT |
| oaire.citation.issue | 4 | pt_PT |
| oaire.citation.startPage | 273 | pt_PT |
| oaire.citation.volume | 15 | pt_PT |
| rcaap.rights | openAccess | pt_PT |
| rcaap.type | article | pt_PT |