Repository logo
 
Publication

Efficacy of Bariatric Surgery in Type 2 Diabetes Mellitus Remission: the Role of Mini Gastric Bypass/One Anastomosis Gastric Bypass and Sleeve Gastrectomy at 1 Year of Follow-up. A European survey

2016-05Journal article Open access
Simple item page
dc.contributor.authorMusella, M
dc.contributor.authorApers, J
dc.contributor.authorRheinwalt, K
dc.contributor.authorRibeiro, R
dc.contributor.authorManno, E
dc.contributor.authorGreco, F
dc.contributor.authorČierny, M
dc.contributor.authorMilone, M
dc.contributor.authorDi Stefano, C
dc.contributor.authorGuler, S
dc.contributor.authorVan Lessen, IM
dc.contributor.authorGuerra, A
dc.contributor.authorMaglio, MN
dc.contributor.authorBonfanti, R
dc.contributor.authorNovotna, R
dc.contributor.authorCoretti, G
dc.contributor.authorPiazza, L
dc.date.accessioned2018-05-22T14:19:24Z
dc.date.available2018-05-22T14:19:24Z
dc.date.issued2016-05
dc.description.abstractBACKGROUND: A retrospective study was undertaken to define the efficacy of both mini gastric bypass or one anastomosis gastric bypass (MGB/OAGB) and sleeve gastrectomy (SG) in type 2 diabetes mellitus (T2DM) remission in morbidly obese patients (pts). METHODS: Eight European centers were involved in this survey. T2DM was preoperatively diagnosed in 313/3252 pts (9.62%). In 175/313 patients, 55.9% underwent MGB/OAGB, while in 138/313 patients, 44.1% received SG between January 2006 and December 2014. RESULTS: Two hundred six out of 313 (63.7 %) pts reached 1 year of follow-up. The mean body mass index (BMI) for MGB/OAGB pts was 33.1 ± 6.6, and the mean BMI for SG pts was 35.9 ± 5.9 (p < 0.001). Eighty-two out of 96 (85.4%) MGB/OAGB pts vs. 67/110 (60.9%) SG pts are in remission (p < 0.001). No correlation was found in the % change vs. baseline values for hemoglobin A1c (HbA1c) and fasting plasma glucose (FPG) in relation to BMI reduction, for both MGB/OAGB or SG (ΔFPG 0.7 and ΔHbA1c 0.4 for MGB/OAGB; ΔFPG 0.7 and ΔHbA1c 0.1 for SG). At multivariate analysis, high baseline HbA1c [odds ratio (OR) = 0.623, 95% confidence interval (CI) 0.419-0.925, p = 0.01], preoperative consumption of insulin or oral antidiabetic agents (OR = 0.256, 95% CI 0.137-0.478, p = <0.001), and T2DM duration >10 years (OR = 0.752, 95% CI 0.512-0.976, p = 0.01) were negative predictors whereas MGB/OAGB resulted as a positive predictor (OR = 3.888, 95% CI 1.654-9.143, p = 0.002) of diabetes remission. CONCLUSIONS: A significant BMI decrease and T2DM remission unrelated from weight loss were recorded for both procedures if compared to baseline values. At univariate and multivariate analyses, MGB/OAGB seems to outperform significantly SG. Four independent variables able to influence T2DM remission at 12 months have been identified.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationObes Surg. 2016 May;26(5):933-40.pt_PT
dc.identifier.doi10.1007/s11695-015-1865-6pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2977
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Verlagpt_PT
dc.subjectAdultpt_PT
dc.subjectDiabetes Mellitus, Type 2pt_PT
dc.subjectFemalept_PT
dc.subjectFollow-Up Studiespt_PT
dc.subjectGastrectomypt_PT
dc.subjectGastric Bypasspt_PT
dc.subjectHealth Surveyspt_PT
dc.subjectHumanspt_PT
dc.subjectMalept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectObesity, Morbidpt_PT
dc.subjectRetrospective Studiespt_PT
dc.subjectTreatment Outcomept_PT
dc.subjectWeight Losspt_PT
dc.subjectCHLC CIRpt_PT
dc.titleEfficacy of Bariatric Surgery in Type 2 Diabetes Mellitus Remission: the Role of Mini Gastric Bypass/One Anastomosis Gastric Bypass and Sleeve Gastrectomy at 1 Year of Follow-up. A European surveypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage940pt_PT
oaire.citation.issue5pt_PT
oaire.citation.startPage933pt_PT
oaire.citation.titleObesity Surgerypt_PT
oaire.citation.volume26pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Obes Surg 2016 933.pdf
Size:
509.46 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

CIR - Artigos