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Bull's Eye Maculopathy in a Patient Treated with Efavirenz

dc.contributor.authorVaz Pereira, C
dc.contributor.authorFranco, M
dc.contributor.authorGuerra Pinto, R
dc.contributor.authorLino, S
dc.contributor.authorMaltez, F
dc.contributor.authorBarrão, S
dc.contributor.authorFilipe, H
dc.date.accessioned2015-06-12T14:43:20Z
dc.date.available2015-06-12T14:43:20Z
dc.date.issued2014
dc.description.abstractObjective: To report a case of retinal toxicity associated with efavirenz in an adult. Methods: We describe a case of gradual-onset blurry vision in both eyes in a 37-year-old HIV Caucasian woman, on antiretroviral therapy (ART), including efavirenz. Results: The patient presented with a best corrected visual acuity of 20/100 for the right eye (RE) and 20/125 for the left eye (LE). Fundoscopy revealed mottled atrophic changes of the macular retinal pigment epithelium (RPE) in both eyes. Fluorescein angiography revealed an annular pattern of RPE atrophy in both eyes. Full-field electretinography (ERG) was normal. Conclusions: Based on our patient’s history and on previous reports, efavirenz seems to be the culprit in this case. Our report provides evidence in support of routine ophthalmological evaluation of patients on efavirenz.por
dc.identifier.citationOftalmologia. 2014 Out-Dez; 38 (4): 287-290por
dc.identifier.urihttp://hdl.handle.net/10400.17/2227
dc.language.isoengpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Oftalmologiapor
dc.subjectHCC INFpor
dc.subjectHIVpor
dc.subjectRetinal Pigment Epitheliumpor
dc.subjectToxicitypor
dc.titleBull's Eye Maculopathy in a Patient Treated with Efavirenzpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage290por
oaire.citation.startPage287por
oaire.citation.titleOftalmologiapor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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