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Beyond Self-Monitored Plasma Glucose and HbA1c: the Role of Non-Traditional Glycaemic Markers in Gestational Diabetes Mellitus

dc.contributor.authorMendes, N
dc.contributor.authorTavares Ribeiro, R
dc.contributor.authorSerrano, F
dc.date.accessioned2018-11-29T15:14:24Z
dc.date.available2018-11-29T15:14:24Z
dc.date.issued2018-08
dc.description.abstractStrict glycaemic management is the cornerstone of metabolic control in gestational diabetes mellitus (GDM). Current monitoring standards involve self-monitoring plasma glucose (SMBG) and haemoglobin A1c (HbA1c). However, both have important limitations. SMBG only reflects instantaneous blood glucose and the inconvenience of self-collecting blood frequently results in poor compliance. HbA1c provides information on blood glucose levels from the previous 2 to 3 months and it is influenced by iron-deficient states, common during pregnancy. There is an urgent need for new shorter-term glycaemic markers, as glycated albumin, fructosamine or 1,5-anhydroglucitol. Glycated albumin seems especially interesting as it provides information on blood glucose levels over the foregoing 2-3 weeks and it is not influenced by iron deficiency or the dilutional anaemia of pregnancy. Fructosamine has a precise and inexpensive measurement and it is not affected by haemoglobin characteristics. This review further discusses the potential value of these non-traditional indicators of glycaemic control in patients with GDM, outlining their possible future applications.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Obstet Gynaecol. 2018 Aug;38(6):762-769.pt_PT
dc.identifier.doi10.1080/01443615.2017.1412409pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3110
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherTaylor & Francispt_PT
dc.subjectAdultpt_PT
dc.subjectBiomarkerspt_PT
dc.subjectBlood Glucosept_PT
dc.subjectBlood Glucose Self-Monitoringpt_PT
dc.subjectDeoxyglucosept_PT
dc.subjectDiabetes, Gestationalpt_PT
dc.subjectFemalept_PT
dc.subjectFructosaminept_PT
dc.subjectGlycated Hemoglobin Apt_PT
dc.subjectHumanspt_PT
dc.subjectMaternal Serum Screening Testspt_PT
dc.subjectPregnancypt_PT
dc.subjectSerum Albuminpt_PT
dc.subjectMAC MED MAFpt_PT
dc.titleBeyond Self-Monitored Plasma Glucose and HbA1c: the Role of Non-Traditional Glycaemic Markers in Gestational Diabetes Mellituspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage769pt_PT
oaire.citation.issue6pt_PT
oaire.citation.startPage762pt_PT
oaire.citation.titleJournal of Obstetrics and Gynaecologypt_PT
oaire.citation.volume38pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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