Publication
Intravenous Immunoglobulin for the Treatment of Quetiapin-Induced Bullous Pemphigoid in an HIV-Infected Patient
| dc.contributor.author | Cabete, J | |
| dc.contributor.author | Santos, G | |
| dc.contributor.author | Páris, F | |
| dc.contributor.author | Serrão, V | |
| dc.contributor.author | Fidalgo, A | |
| dc.date.accessioned | 2014-02-10T17:26:56Z | |
| dc.date.available | 2014-02-10T17:26:56Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | The authors present the case of a 48-year-old woman with HIV-associated dementia treated with antiretroviral therapy and psychoactive drugs, to whom bullous pemphigoid(BP) was diagnosed. Given incomplete response to corticotherapy, and azathioprine-induced bicytopenia,intravenous immunoglobulin(IVIG) was initiated. Despite transient disease control, recurrent flares suggested a persistent triggering factor. Specifically, quetiapin was implicated and discontinued with an immediate clinical response. Inadvertent re-challenge with olanzapine(a related drug)led to a new eruption, confirming drug-induced BP (DIBP). A total of six IVIG cycles were completed, without severe side effects to report, namely HIV disease progression. HIV-related autoimmune bullous diseases are rare. Treatment of severe drug eruptions is primarily based on immunossupressive drugs, raising concerns regarding additional immunossupression. This case suggests IVIG as a valuable option for the treatment of BP in HIV patients. In addition, quetiapin should be added to the list of neuroleptics previously linked to DIBP. | por |
| dc.identifier.citation | IN: 71st Annual Meeting of the American Academy of Dermatology; 2013, Março. Miami, EUA | por |
| dc.identifier.uri | http://hdl.handle.net/10400.17/1655 | |
| dc.language.iso | eng | por |
| dc.publisher | Serviço de Dermatologia do Hospital dos Capuchos, Centro Hospitalar de Lisboa Central, EPE | por |
| dc.subject | HSAC DER | por |
| dc.subject | HIV | por |
| dc.subject | Imunoglobulinas Intravenosas | por |
| dc.subject | Penfigoide Bolhoso | por |
| dc.title | Intravenous Immunoglobulin for the Treatment of Quetiapin-Induced Bullous Pemphigoid in an HIV-Infected Patient | por |
| dc.type | other | |
| dspace.entity.type | Publication | |
| rcaap.rights | openAccess | por |
| rcaap.type | other | por |