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Valor Prognóstico da Normalização da Resposta Ventilatória ao Exercício para o Consumo Máximo de Oxigénio na Insuficiência Cardíaca

dc.contributor.authorToste, A
dc.contributor.authorSoares, RM
dc.contributor.authorFeliciano, J
dc.contributor.authorAndreozzi, V
dc.contributor.authorSilva, S
dc.contributor.authorAlves, S
dc.contributor.authorFerreira, ML
dc.contributor.authorAbreu, A
dc.contributor.authorCruz Ferreira, R
dc.date.accessioned2011-06-22T12:37:43Z
dc.date.available2011-06-22T12:37:43Z
dc.date.issued2010
dc.description.abstractCardiopulmonary exercise testing (CPET) is an objective method for assessment of functional capacity and for prognostic stratification of patients with chronic heart failure (CHF). In this study, we analyzed the prognostic value of a recently described CPET-derived parameter, the minute ventilation to carbon dioxide production slope normalized for peak oxygen consumption (VE/VCO2 slope/pVO2). METHODS: We prospectively studied 157 patients with stable CHF and dilated cardiomyopathy who performed maximal CPET using the modified Bruce protocol. The prognostic value of VE/VCO2 slope/pVO2 was determined and compared with traditional CPET parameters. RESULTS: During follow-up 37 patients died and 12 were transplanted. Mean follow-up in surviving patients was 29.7 months (12-36). Cox multivariate analysis revealed that VE/VCO2 slope/pVO2 had the greatest prognostic power of all the parameters studied. A VE/VCO2 slope/pVO2 of > or = 2.2 signaled cases at higher risk. CONCLUSION: Normalization of the ventilatory response to exercise for peak oxygen consumption appears to increase the prognostic value of CPET in patients with CHF.por
dc.identifier.citationRev Port Cardiol. 2010 Sep;29(9):1305-20por
dc.identifier.urihttp://hdl.handle.net/10400.17/276
dc.language.isoporpor
dc.peerreviewedyespor
dc.publisherSociedade Portuguesa de Cardiologiapor
dc.subjectDoença Crónicapor
dc.subjectProva de Esforçopor
dc.subjectInsuficiência Cardíacapor
dc.subjectConsumo de Oxigéniopor
dc.subjectPrognósticopor
dc.subjectEstudos Prospectivospor
dc.titleValor Prognóstico da Normalização da Resposta Ventilatória ao Exercício para o Consumo Máximo de Oxigénio na Insuficiência Cardíacapor
dc.title.alternativeCombining Ventilatory Efficiency and Peak Oxygen Consumption in the Prognostic Assessment of Patients with Chronic Heart Failurepor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1320por
oaire.citation.startPage1305por
oaire.citation.titleRevista Portuguesa de Cardiologiapor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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