Endobronchial Amphotericin B to Treat Hemoptysis in an Inoperable Patient with Aspergillosis

Pinto, M; Rodrigues, J; Silva, M; Maia, D; Miguel, A

http://hdl.handle.net/10400.17/4913

Use this identifier to reference this record.

Name:	Description:	Size:	Format:
Med Mycol Case Rep 2024_100627.pdf		3.82 MB	Adobe PDF	Download

Send Feedback

Authors

Abstract(s)

A 37-year-old man presented with chronic cavitary pulmonary aspergillosis and hemoptysis refractory to systemic antifungal therapy with voriconazole and bronchial artery embolization. Surgical excision was unfeasible due to the patient's refusal of blood transfusions. Ten sessions of intracavitary instillation of amphotericin B via flexible bronchoscopy were then performed. Hemoptysis cessation and aspergilloma resolution were achieved, with no toxicity or side effects, and the clinical benefits were sustained at six months of follow-up.