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Changes in Surgical Revascularization Strategy After Fractional Flow Reserve

2021Journal article Open access
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dc.contributor.authorFournier, S
dc.contributor.authorToth, G
dc.contributor.authorDe Bruyne, B
dc.contributor.authorKala, P
dc.contributor.authorRibichini, F
dc.contributor.authorCasselman, F
dc.contributor.authorRamos, R
dc.contributor.authorPiroth, Z
dc.contributor.authorPiccoli, A
dc.contributor.authorPenicka, M
dc.contributor.authorMates, M
dc.contributor.authorNemec, P
dc.contributor.authorVan Praet, F
dc.contributor.authorStockman, B
dc.contributor.authorDegriek, I
dc.contributor.authorPellicano, M
dc.contributor.authorBarbato, E
dc.date.accessioned2024-03-08T16:16:25Z
dc.date.available2024-03-08T16:16:25Z
dc.date.issued2021
dc.description.abstractAims: In the randomized GRAFFITI trial, surgeons drew their strategy based on coronary angiography. When patients were randomized to fractional flow reserve (FFR)-guidance, surgeons were informed of the FFR values and asked to redraw their strategy. The aim of this study was to investigate the changes induced by FFR knowledge. Methods and results: The intended and performed strategy (before and after FFR) were compared. Among 172 patients, 84 with 300 lesions were randomized to the FFR-guided group. The intended strategy was to bypass 236 stenoses:108 with a venous and 128 with an arterial graft. After disclosing FFR, a change in strategy occurred in 64 lesions (21.3%) of 48 (55%) patients. Among 64 lesions for which the intended strategy was medical therapy, 16 (25%) were bypassed after disclosing FFR. The number of procedures with >1 venous graft planned was significantly reduced from 37 to 27 patients (p = .031). The proportion of on-pump surgery was significantly reduced from 71 to 61 patients (p = .006). The rates of clinical events at 1 year were similar between patients with or without at least one change in strategy. Discussion: FFR-guided CABG is associated with a simplified surgical procedure in 55% of the patients, with similar clinical outcomes.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationCatheter Cardiovasc Interv . 2021 Sep;98(3):E351-E355.pt_PT
dc.identifier.doi10.1002/ccd.29694pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4833
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherWileypt_PT
dc.subjectHSM CARpt_PT
dc.subjectCoronary Angiographypt_PT
dc.subjectHumanspt_PT
dc.subjectTreatment Outcomept_PT
dc.subjectCoronary Artery Bypass / adverse effectspt_PT
dc.subjectCoronary Artery Disease* / diagnostic imagingpt_PT
dc.subjectCoronary Artery Disease* / surgerypt_PT
dc.subjectCoronary Stenosis* / diagnostic imagingpt_PT
dc.subjectCoronary Stenosis* / surgerypt_PT
dc.subjectFollow-Up Studiespt_PT
dc.subjectFractional Flow Reserve, Myocardial*pt_PT
dc.titleChanges in Surgical Revascularization Strategy After Fractional Flow Reservept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPageE355pt_PT
oaire.citation.issue3pt_PT
oaire.citation.startPageE351pt_PT
oaire.citation.titleCatheterization and Cardiovascular Interventionspt_PT
oaire.citation.volume98pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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