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Comparative Performance of Screening Instruments for Obstructive Sleep Apnea in Morbidly Obese Patients Referred to a Sleep Laboratory: a Prospective Cross-Sectional Study

dc.contributor.authorDuarte, R
dc.contributor.authorMello, F
dc.contributor.authorMagalhães-da-Silveira, F
dc.contributor.authorOliveira e Sá, T
dc.contributor.authorRabahi, M
dc.contributor.authorGozal, D
dc.date.accessioned2021-09-08T12:10:34Z
dc.date.available2021-09-08T12:10:34Z
dc.date.issued2019
dc.description.abstractPurpose: Obstructive sleep apnea (OSA) is very common occurrence among morbidly obese patients. Our main objectives were to validate the No-Apnea, a 2-item screening tool, in morbidly obese patients and compare its performance with three other instruments: STOP-Bang questionnaire, NoSAS score, and Epworth Sleepiness Scale (ESS). Methods: A cross-sectional analysis of morbidly obese patients (body mass index [BMI] ≥ 35.0 kg/m2) grouped into two independent samples: bariatric surgery patients (BS) and non-bariatric surgery patients (NBS). All patients underwent overnight polysomnography. Discriminatory ability was assessed by area under the curve (AUC). OSA severity was defined by apnea/hypopnea index cut-off points: ≥ 5.0/h (OSA≥5), ≥ 15.0/h (OSA≥15), and ≥ 30.0/h (OSA≥30). Results: A total of 1017 subjects (40.4% in BS cohort and 59.6% in NBS cohort) were evaluated. In the BS cohort, No-Apnea had similar discrimination to STOP-Bang and NoSAS for predicting OSA≥5 (p = 0.979 and p = 0.358, respectively), OSA≥15 (p = 0.158 and p = 0.399, respectively), and OSA≥30 (p = 0.388 and p = 0.903, respectively). In the NBS cohort, No-Apnea had similar discrimination to STOP-Bang and NoSAS for predicting OSA≥5 (p = 0.528 and p = 0.428, respectively), OSA≥15 (p = 0.825 and p = 0.108, respectively), and OSA≥30 (p = 0.458 and p = 0.186, respectively). Moreover, No-Apnea performed significantly better than ESS in both BS and NBS cohorts (p < 0.001). Conclusions: No-Apnea is a useful and practical tool for screening of OSA in morbidly obese patients, with non-inferior performance to STOP-Bang questionnaire and NoSAS score.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSleep Breath. 2019 Dec;23(4):1123-1132.pt_PT
dc.identifier.doi10.1007/s11325-019-01791-w.pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3846
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringerpt_PT
dc.subjectHSM PNEUpt_PT
dc.subjectAdultpt_PT
dc.subjectFemalept_PT
dc.subjectMalept_PT
dc.subjectHumanspt_PT
dc.subjectBariatric Surgerypt_PT
dc.subjectCohort Studiespt_PT
dc.subjectCross-Sectional Studiespt_PT
dc.subjectMiddle Agedpt_PT
dc.subjectMass Screeningpt_PT
dc.subjectObesity, Morbid / diagnosispt_PT
dc.subjectObesity, Morbid / physiopathologypt_PT
dc.subjectPolysomnographypt_PT
dc.subjectProspective Studiespt_PT
dc.subjectReferral and Consultationpt_PT
dc.subjectSleep Apnea, Obstructive / diagnosispt_PT
dc.subjectSleep Apnea, Obstructive / physiopathologypt_PT
dc.subjectSurveys and Questionnairespt_PT
dc.titleComparative Performance of Screening Instruments for Obstructive Sleep Apnea in Morbidly Obese Patients Referred to a Sleep Laboratory: a Prospective Cross-Sectional Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1132pt_PT
oaire.citation.startPage1123pt_PT
oaire.citation.titleSleep and Breathingpt_PT
oaire.citation.volume23pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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