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Diagnostic Challenge in a Sickle Cell Disease Patient with COVID-19

dc.contributor.authorRodrigues, J
dc.contributor.authorSilva, TM
dc.contributor.authorGarcia, AM
dc.contributor.authorSoares, E
dc.contributor.authorBrito, MJ
dc.date.accessioned2022-11-15T15:40:49Z
dc.date.available2022-11-15T15:40:49Z
dc.date.issued2022
dc.description.abstractAcute chest syndrome is a life-threatening complication in sickle cell disease. Infections are frequently implied, and like other viruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be a trigger. In addition, due to their inflammatory status, they may present a higher risk for severe coronavirus disease 2019 (COVID-19). Pneumonia and acute chest syndrome share clinical, laboratory, and radiological features and may overlap, which makes their differential diagnosis especially challenging. We describe a case of an adolescent with homozygous sickle cell disease that developed acute chest syndrome in the context of COVID-19. With it, we intend to bring awareness to the potential role of imaging in the differential diagnosis and in establishing the best approach for the patient. Chest computed tomography findings were suggestive of an alternative diagnosis to COVID-19 pneumonia and red cell transfusion, fluid management, analgesics, and antibiotics were administered with favorable outcome.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPort J Pediatr 2022;53:435-9pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4280
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSociedade Portuguesa de Pediatriapt_PT
dc.subjectAcute Chest Syndrome/diagnosispt_PT
dc.subjectAcute Chest Syndrome/diagnostic imagingpt_PT
dc.subjectAcute Chest Syndrome/therapypt_PT
dc.subjectAnemia, Sickle Cell/ complicationspt_PT
dc.subjectCOVID-19/complicationspt_PT
dc.subjectDiagnosis, Differentialpt_PT
dc.subjectSARS-CoV-2pt_PT
dc.subjectTomography, X-ray Computedpt_PT
dc.subjectAdolescentpt_PT
dc.subjectHDE IMApt_PT
dc.subjectHDE INF PEDpt_PT
dc.titleDiagnostic Challenge in a Sickle Cell Disease Patient with COVID-19pt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage439pt_PT
oaire.citation.startPage435pt_PT
oaire.citation.volume53pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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