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Defeitos do Tubo Neural. Experiência de 10 Anos numa Maternidade Central

dc.contributor.authorTeixeira, AL
dc.contributor.authorLoreto, H
dc.contributor.authorMachado, MC
dc.contributor.authorRamos de Almeida, JM
dc.date.accessioned2012-08-30T14:35:16Z
dc.date.available2012-08-30T14:35:16Z
dc.date.issued1994
dc.description.abstractOBJECTIVES: 1) To determine trends in prevalence of neural tube defects and the impact of therapeutic abortion. 2) To review perinatal management of spina bifida. DESIGN: All spontaneous and therapeutic abortions, still births and live births affected by neural tube defects registered in Alfredo da Costa Maternity in Lisbon, from 1983 to 1992, were retrospectively analysed. RESULTS: Eighty-two cases with neural tube defects are reported and myelomeningocele and anencephaly++ were the most frequent ones. Total prevalence for all defects was 0.78:1000 births with a small upward trend during the last two years. Birth prevalence was 0.6:1000, with a clear downward trend, due to therapeutic abortion. Prenatal diagnosis improved significantly, from 9% of all defects detected in 1983-87 to 77.5% in 1988-92. Since 1989, all cases of anencephaly were detected before birth. Most cases of spina bifida were vaginally delivered, and elective cesarean section occurred in 4. Early closure of the defect was undertaken in 87.6% of the newborns with open spina bifida. CONCLUSION: While total prevalence of neural tube defects remained stable, with only a small upward trend, prenatal diagnosis and therapeutic abortion resulted in a 56.3% fall in birth prevalence. Optimal management of open spina bifida demands a multidisciplinary team with an individual program for each case.por
dc.identifier.citationActa Med Port. 1994 Jul-Aug;7(7-8):419-25por
dc.identifier.urihttp://hdl.handle.net/10400.17/631
dc.language.isoporpor
dc.peerreviewedyespor
dc.publisherCentro Editor e Livreiro da Ordem dos Médicospor
dc.subjectDoenças Fetaispor
dc.subjectMaternidade Dr. Alfredo da Costapor
dc.subjectEstatísticapor
dc.subjectDefeitos do Tubo Neuralpor
dc.subjectPortugalpor
dc.subjectGravidezpor
dc.subjectDiagnóstico Pré-Natalpor
dc.subjectPrevalênciapor
dc.subjectEstudos Retrospectivospor
dc.subjectMAC PED
dc.titleDefeitos do Tubo Neural. Experiência de 10 Anos numa Maternidade Centralpor
dc.title.alternativeNeural Tube Defects. The 10-Year Experience of a Central Maternity Hospitalpor
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage425por
oaire.citation.startPage419por
oaire.citation.titleActa Médica Portuguesapor
rcaap.rightsopenAccesspor
rcaap.typearticlepor

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