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Esophageal and Gastric Malignancies After Bariatric Surgery: a Retrospective Global Study

2022-04Journal article Open access
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dc.contributor.authorParmar, C
dc.contributor.authorZakeri, R
dc.contributor.authorAbouelazayem, M
dc.contributor.authorShin, T
dc.contributor.authorAminian, A
dc.contributor.authorMahmoud, T
dc.contributor.authorAbu Dayyeh, B
dc.contributor.authorWee, M
dc.contributor.authorFischer, L
dc.contributor.authorDaams, F
dc.contributor.authorMahawar, K
dc.contributor.authorGallardo, C
dc.contributor.authorAgustin, C
dc.contributor.authorWright, F
dc.contributor.authorFuente, I
dc.contributor.authorCarbajo, M
dc.contributor.authorCal, P
dc.contributor.authorChisholm, J
dc.contributor.authorKow, L
dc.contributor.authorTan, M
dc.contributor.authorGan, P
dc.contributor.authorGananadha, S
dc.contributor.authorFelsenreich, D
dc.contributor.authorPrager, G
dc.contributor.authorMatthys, C
dc.contributor.authorHimpens, J
dc.contributor.authorFocquet, M
dc.contributor.authorRamos, A
dc.contributor.authorNato, M
dc.contributor.authorVidal, T
dc.contributor.authorAndalib, A
dc.contributor.authorSiblini, A
dc.contributor.authorFerri, L
dc.contributor.authorAbdarabo, L
dc.contributor.authorNevo, Y
dc.contributor.authorPescarus, R
dc.contributor.authorYang, W
dc.contributor.authorHamed, H
dc.contributor.authorLiagre, A
dc.contributor.authorBergeat, D
dc.contributor.authorMarie, De M
dc.contributor.authorMartini, F
dc.contributor.authorRegis, F
dc.contributor.authorGenser, L
dc.contributor.authorSkalli, M
dc.contributor.authorNedelcu, M
dc.contributor.authorSmejkal, M
dc.contributor.authorKassir, R
dc.contributor.authorNicolas, R
dc.contributor.authorStier, C
dc.contributor.authorNedelcut, DS
dc.contributor.authorChristodoulidis, G
dc.contributor.authorVennapusa, A
dc.contributor.authorKermansaravi, M
dc.contributor.authorRaziel, A
dc.contributor.authorSakran, N
dc.contributor.authorOldani, A
dc.contributor.authorBoru, C
dc.contributor.authorMécheri, F
dc.contributor.authorCiccarese, F
dc.contributor.authorCesana, G
dc.contributor.authorMusella, M
dc.contributor.authorUccelli, M
dc.contributor.authorFoletto, M
dc.contributor.authorAuricchio, P
dc.contributor.authorOlmi, S
dc.contributor.authorSeki, Y
dc.contributor.authorKasteleijn, A
dc.contributor.authorVan 'T Hof, G
dc.contributor.authorApers, J
dc.contributor.authorHart, J
dc.contributor.authorVan De Sande, J
dc.contributor.authorTakkenberg, M
dc.contributor.authorFeskens, P
dc.contributor.authorSnoekx, R
dc.contributor.authorPlat, V
dc.contributor.authorSandvik, J
dc.contributor.authorKalinowski, P
dc.contributor.authorNabais, C
dc.contributor.authorAl-Bahrani, A
dc.contributor.authorAl Zoubi, M
dc.contributor.authorBettonica, C
dc.contributor.authorOsorio, J
dc.contributor.authorTejedor-Tejada, J
dc.contributor.authorSanz, L
dc.contributor.authorCuadrado, M
dc.contributor.authorMoorjani, R
dc.contributor.authorYannick, F
dc.contributor.authorSuter, M
dc.contributor.authorBorbély, Y
dc.contributor.authorJoerg, Z
dc.contributor.authorBarajas-Gamboa, J
dc.contributor.authorKroh, M
dc.contributor.authorKisiel, A
dc.contributor.authorKamocka, A
dc.contributor.authorImmanuel, A
dc.contributor.authorSgromo, B
dc.contributor.authorGopinath, B
dc.contributor.authorKhoo, D
dc.contributor.authorMukherjee, S
dc.contributor.authorPournaras, D
dc.contributor.authorUnderwood, T
dc.contributor.authorGriffiths, E
dc.contributor.authorMiller, G
dc.contributor.authorJaretzke, H
dc.contributor.authorDmitrewski, J
dc.contributor.authorWadley, M
dc.contributor.authorAl-Housni, R
dc.contributor.authorGillies, R
dc.contributor.authorSinghal, R
dc.contributor.authorPreston, S
dc.contributor.authorRobinson, S
dc.contributor.authorHawkins, W
dc.contributor.authorAdamo, M
dc.contributor.authorEl Kalaawy, M
dc.contributor.authorGossage, J
dc.contributor.authorCrawford, C
dc.contributor.authorJaruvongvanich, V
dc.date.accessioned2023-12-05T15:23:14Z
dc.date.available2023-12-05T15:23:14Z
dc.date.issued2022-04
dc.description.abstractBackground: Bariatric surgery can influence the presentation, diagnosis, and management of gastrointestinal cancers. Esophagogastric (EG) malignancies in patients who have had a prior bariatric procedure have not been fully characterized. Objective: To characterize EG malignancies after bariatric procedures. Setting: University Hospital, United Kingdom. Methods: We performed a retrospective, multicenter observational study of patients with EG malignancies after bariatric surgery to characterize this condition. Results: This study includes 170 patients from 75 centers in 25 countries who underwent bariatric procedures between 1985 and 2020. At the time of the bariatric procedure, the mean age was 50.2 ± 10 years, and the mean weight 128.8 ± 28.9 kg. Women composed 57.3% (n = 98) of the population. Most (n = 64) patients underwent a Roux-en-Y gastric bypass (RYGB) followed by adjustable gastric band (AGB; n = 46) and sleeve gastrectomy (SG; n = 43). Time to cancer diagnosis after bariatric surgery was 9.5 ± 7.4 years, and mean weight at diagnosis was 87.4 ± 21.9 kg. The time lag was 5.9 ± 4.1 years after SG compared to 9.4 ± 7.1 years after RYGB and 10.5 ± 5.7 years after AGB. One third of patients presented with metastatic disease. The majority of tumors were adenocarcinoma (82.9%). Approximately 1 in 5 patients underwent palliative treatment from the outset. Time from diagnosis to mortality was under 1 year for most patients who died over the intervening period. Conclusion: The Oesophago-Gastric Malignancies After Obesity/Bariatric Surgery study presents the largest series to date of patients developing EG malignancies after bariatric surgery and attempts to characterize this condition.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationSurg Obes Relat Dis . 2022 Apr;18(4):464-472.pt_PT
dc.identifier.doi10.1016/j.soard.2021.11.024pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/4755
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherElsevierpt_PT
dc.subjectHSJ CIRpt_PT
dc.subjectAdultpt_PT
dc.subjectHumanspt_PT
dc.subjectFemalept_PT
dc.subjectMiddle Agedpt_PT
dc.subjectBariatric Surgery* / adverse effectspt_PT
dc.subjectBariatric Surgery* / methodspt_PT
dc.subjectGastrectomy / adverse effectspt_PT
dc.subjectGastrectomy / methodspt_PT
dc.subjectGastric Bypass* / adverse effectspt_PT
dc.subjectGastric Bypass* / methodspt_PT
dc.subjectObesity, Morbid* / surgerypt_PT
dc.subjectRetrospective Studiespt_PT
dc.subjectStomach Neoplasms* / epidemiologypt_PT
dc.subjectStomach Neoplasms* / etiologypt_PT
dc.subjectStomach Neoplasms* / surgerypt_PT
dc.subjectTreatment Outcomept_PT
dc.titleEsophageal and Gastric Malignancies After Bariatric Surgery: a Retrospective Global Studypt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage472pt_PT
oaire.citation.issue4pt_PT
oaire.citation.startPage464pt_PT
oaire.citation.titleSurgery for Obesity and Related Diseasespt_PT
oaire.citation.volume18pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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