Anti-N-Methyl-D-Aspartate Receptor Encephalitis with Positive Serum Antithyroid Antibodies, IgM Antibodies Against Mycoplasma Pneumoniae and Human Herpesvirus 7 PCR in the CSF

Venâncio, P; Brito, MJ; Pereira, G; Vieira, JP

http://hdl.handle.net/10400.17/2524

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Abstract(s)

We report the case of a boy with an encephalopathy associated with extrapyramidal and psychiatric symptoms and anti-N-methyl-D-aspartate receptor antibodies. He had positive serum antithyroid antibodies, IgM antibodies against Mycoplasma pneumoniae and human herpesvirus 7 polymerase chain reaction in the cerebrospinal fluid. He was successfully treated with rituximab, after steroids, intravenous immunoglobulin and plasma exchange. The pathophysiology of this disorder may be post-infectious and autoimmune.

Keywords

Anti-N-Methyl-D-Aspartate Receptor Encephalitis Antibodies, Bacterial Antibodies, Monoclonal, Murine-Derived Antibodies, Viral Autoantibodies Child Herpesvirus 7, Human Humans Immunoglobulin M Immunologic Factors Male Mycoplasma pneumoniae Rituximab HDE INF PED HDE UCI PED HDE NEU PED