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Acoustic and Clinical Data Analysis of Vocal Recordings: Pandemic Insights and Lessons.

dc.contributor.authorCarreiro-Martins, Pedro
dc.contributor.authorPaixão, Paulo
dc.contributor.authorCaires, Iolanda
dc.contributor.authorMatias, Pedro
dc.contributor.authorGamboa, Hugo
dc.contributor.authorSoares, Filipe
dc.contributor.authorGomez, Pedro
dc.contributor.authorSousa, Joana
dc.contributor.authorNeuparth, Nuno
dc.date.accessioned2025-07-25T13:51:28Z
dc.date.available2025-07-25T13:51:28Z
dc.date.issued2024-10-12
dc.description.abstractBackground/Objectives: The interest in processing human speech and other human-generated audio signals as a diagnostic tool has increased due to the COVID-19 pandemic. The project OSCAR (vOice Screening of CoronA viRus) aimed to develop an algorithm to screen for COVID-19 using a dataset of Portuguese participants with voice recordings and clinical data. Methods: This cross-sectional study aimed to characterise the pattern of sounds produced by the vocal apparatus in patients with SARS-CoV-2 infection documented by a positive RT-PCR test, and to develop and validate a screening algorithm. In Phase II, the algorithm developed in Phase I was tested in a real-world setting. Results: In Phase I, after filtering, the training group consisted of 166 subjects who were effectively available to train the classification model (34.3% SARS-CoV-2 positive/65.7% SARS-CoV-2 negative). Phase II enrolled 58 participants (69.0% SARS-CoV-2 positive/31.0% SARS-CoV-2 negative). The final model achieved a sensitivity of 85%, a specificity of 88.9%, and an F1-score of 84.7%, suggesting voice screening algorithms as an attractive strategy for COVID-19 diagnosis. Conclusions: Our findings highlight the potential of a voice-based detection strategy as an alternative method for respiratory tract screening.eng
dc.identifier.citationDiagnostics (Basel) . 2024 Oct 12;14(20):2273
dc.identifier.doi10.3390/diagnostics14202273
dc.identifier.other39451596
dc.identifier.urihttp://hdl.handle.net/10400.17/5123
dc.language.isoen
dc.peerreviewedyes
dc.publisherMDPI
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.subjectSARS-CoV-2
dc.subjectdiagnostic tests
dc.subjectmachine learning
dc.subjectspeech
dc.subjectvoice
dc.subjectHDE ALER
dc.titleAcoustic and Clinical Data Analysis of Vocal Recordings: Pandemic Insights and Lessons.
dc.typetext
dspace.entity.typePublication
oaire.citation.issue20
oaire.citation.startPage2273
oaire.citation.volume14
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85

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