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HELLP Syndrome a Severe Form of Preeclampsia: a Comparative Study of Clinical and Laboratorial Parameters

dc.contributor.authorCampos, A
dc.contributor.authorGonçalves, A
dc.contributor.authorMassa, AC
dc.contributor.authorAmaral, P
dc.contributor.authorSilva, P
dc.contributor.authorAguilar, S
dc.date.accessioned2016-07-12T15:22:00Z
dc.date.available2016-07-12T15:22:00Z
dc.date.issued2016
dc.description.abstractThe objective of this study was to compare clinical, laboratorial, maternal and perinatal results between HELLP Syndrome and severe Preeclampsia. An observational study comparing women with HELLP Syndrome (n=71) to women with severe preeclampsia (n=253) was done. The authors analyzed the early course of the pathologies and the outcomes in both groups. HELLP syndrome occurred in 28% of all the cases and was more frequent at gestational age before 32 weeks (n=39 – 55%) than severe preeclampsia (n=108 - 42%), with more newborns weighting less than 1500g (27 – 38.6% vs 65 – 25.6%; p=0.036). Thrombocytopenia below 100 000/μL (aOR, 2.14; 95% CI, 1.49 – 3.06) and LDH>1 000 UI/L (aOR: 5.17; 95% CI 2.19 – 12.16) were risk factors for HELLP. Maternal morbidity (eclampsia, abruptio placentae, and acute renal failure) was similar in both cohorts; eight stillbirths (6 in severe preeclampsia and 2 in HELLP Syndrome) occurred. There were no maternal deaths. In conclusion, in this study the authors confirmed that HELLP Syndrome is a severe form of preeclampsia with an earlier presentation in pregnancy, worst laboratorial findings and more prematurity rates.pt_PT
dc.identifier.citationAm J Exp Clin Res 2016; 3(3): 170-174pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/2543
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectMAC MED MAFpt_PT
dc.subjectPre-Eclampsiapt_PT
dc.subjectMorbiditypt_PT
dc.subjectHELLP Syndromept_PT
dc.titleHELLP Syndrome a Severe Form of Preeclampsia: a Comparative Study of Clinical and Laboratorial Parameterspt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage174pt_PT
oaire.citation.startPage170pt_PT
oaire.citation.titleAmerican Journal of Experimental and Clinical Researchpt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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