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Mixed connective tissue disease: state of the art on clinical practice guidelines

2018Journal article Open access
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dc.contributor.authorChaigne, B
dc.contributor.authorScirè, CA
dc.contributor.authorTalarico, R
dc.contributor.authorAlexander, T
dc.contributor.authorAmoura, Z
dc.contributor.authorAvcin, T
dc.contributor.authorBeretta, L
dc.contributor.authorDoria, A
dc.contributor.authorGuffroy, A
dc.contributor.authorGuimarães, V
dc.contributor.authorHachulla, É
dc.contributor.authorKrieg, T
dc.contributor.authorLaunay, D
dc.contributor.authorLepri, G
dc.contributor.authorMoinzadeh, P
dc.contributor.authorMüller-Ladner, U
dc.contributor.authorRednic, S
dc.contributor.authorRodrigues, A
dc.contributor.authorTas, SW
dc.contributor.authorvan Vollenhoven, RF
dc.contributor.authorVieira, A
dc.contributor.authorBombardieri, S
dc.contributor.authorFonseca, JE
dc.contributor.authorGaletti, I
dc.contributor.authorSchneider, M
dc.contributor.authorSmith, V
dc.contributor.authorCutolo, M
dc.contributor.authorMosca, M
dc.contributor.authorFischer-Betz, R
dc.date.accessioned2021-03-22T16:46:31Z
dc.date.available2021-03-22T16:46:31Z
dc.date.issued2018
dc.description.abstractMixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies targeting the U1 small nuclear ribonucleoprotein particle. In this narrative review, we summarise the results of a systematic literature research which was performed as part of the European Reference Network on Rare and Complex Connective Tissue and Musculoskeletal Diseases project, aimed at evaluating existing clinical practice guidelines (CPGs) or recommendations. Since no specific CPGs on MCTD were found, other CPGs developed for other CTDs were taken into consideration in order to discuss what can be applied to MCTD even if designed for other diseases. Three major objectives were proposed for the future development of CPGs: MCTD diagnosis (diagnostic criteria), MCTD initial and follow-up evaluations, MCTD treatment. Early diagnosis, epidemiological data, assessment of burden of disease and QOL aspects are among the unmet needs identified by patients.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationRMD Open . 2018 Oct 18;4(Suppl 1):e000783.pt_PT
dc.identifier.doi10.1136/rmdopen-2018-000783pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.17/3624
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMJ Openpt_PT
dc.subjectERN reconnetpt_PT
dc.subjectClinical practice guidelinespt_PT
dc.subjectEuropean reference networkspt_PT
dc.subjectMixed connective tissue diseasept_PT
dc.subjectHCC DAUTOIMpt_PT
dc.titleMixed connective tissue disease: state of the art on clinical practice guidelinespt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issueSuppl 1pt_PT
oaire.citation.startPagee000783pt_PT
oaire.citation.titleRMD openpt_PT
oaire.citation.volume4pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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